Switching from Remicade to Humira? Did it work for you?

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Regular Member

Date Joined Jan 2006
Total Posts : 449
   Posted 9/7/2008 10:07 PM (GMT -6)   
Looks like Remicade is officially failing me. They have doubled my dose AND increased the frequency to 6 weeks, but as of today, I'm 2 1/2 weeks from my last double dose and I'm having horrible cramping again and seeing blood. I've had to take 2 pain pills today just to function.

I'm calling in the morning and I'm sure Humira is next on the list. I know there is also Cimzia and Tsaybri (sp?), but Humira was the one my GI mentioned last time I was in if this "plan" didn't work. I'm not worried about injections. I've been through 2 In-Vitro Fertilizations and having given myself my own sub-q and IM (intramuscular) injections, so none of the shots worry me, but I'm just a nervous nelly about a new drug and also the fact that "will it work?"

So, if you made the switch..

Did it work?
How long before you noticed it worked?
Any side effects?
Pros of Humira?
Cons of Humira?

Any input is appreciated!
Kaycie - Age: 26
Crohn's - Dx Nov 05
Remicade - Next infusion - July 10th - new dose - 10mg/kg
IVF #1 (In-Vitro Fertilization) - Failed
IVF #2 - IVIg, Heparin, Baby Aspirin - TWIN GIRLS!!!
Reagan Dawn - 8/2/07 - Lived 1 hour 27 minutes due to Cloaca, NOT affiliated with my Crohn's
Addison Maria - 8/2/07 - 11 months old

Regular Member

Date Joined Oct 2007
Total Posts : 241
   Posted 9/7/2008 10:24 PM (GMT -6)   
I am making the switch as well. I am supposed to start Humira in the next couple of weeks. We can compare notes as we go.

Regular Member

Date Joined Oct 2005
Total Posts : 168
   Posted 9/8/2008 12:41 AM (GMT -6)   
I tried it for 6 months and it didn't work for me. now i'm back on remicade.
diagnosed: Crohn's Aug 2005
other set-backs: Vasculitis Aug 2006, Sub-total Colectomy (10 inches of colon left) Feb 2007, Ogilivie's Syndrome Mar 2007, Pulmonary Embolism Sept 2007, Collapsed lung Oct 2007, Recto/Vaginal fistula Nov 2007
drugs: Imuran, Remicade, Prednisone, Fentanyl, Warfarin, Flagyl, Cipro, Celexa, Ferrous Gluconate, Acidopholous

Elite Member

Date Joined Sep 2005
Total Posts : 10404
   Posted 9/8/2008 2:36 AM (GMT -6)   
You can find a few threads about switching from Rem to Humira under the new meds thread. You can find the new meds thread in the Crohn's resources thread, at the top of this forum.

Best wishes,

Co-Moderator Crohn's Forum.

Regular Member

Date Joined May 2007
Total Posts : 69
   Posted 9/8/2008 8:44 AM (GMT -6)   
Hi ! My 18 year old son just switched from Remicade to Humira as he had developed antibodies after a year and a half and on a max dose. He has had the two loading doses and it seems to be working as his ablility to eat and maintain weight has increased and his energy level seems to be improved. I was a little skeptical that it was going to work as well as Remicade had initially seemed to but his improvement already is encouraging. Good luck!!

Regular Member

Date Joined Apr 2007
Total Posts : 345
   Posted 9/8/2008 8:59 AM (GMT -6)   
I am trying to get pregnant. My doctor wants me to stop Remicade for my 3rd trimester (when it crosses the placenta). This would be the 3rd time I've stopped Remicade. I'm wondering if I should make the switch now BEFORE Remicade stops working. I see alot of people post that when Remicade doesnt work, neither does Humira. Maybe it will work better if I switch while Remicade still works.

Kaycie, Keep us informed on your progress.
33 years old. Diagnosed in 2002ish. 
Taking Asacol, Lomotil TID, and on Remicade since 2004. 
Lower Bowel area only, except for the short stint (about 2 weeks) that I had mouth sores.  Also have external/anal fistula and anal/vaginal fistula. 

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