pregnant on azathioprine?

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wibiff
Regular Member


Date Joined Feb 2008
Total Posts : 27
   Posted 9/7/2008 11:09 PM (GMT -6)   
Have any of you gotten pregnant on azathioprine?  I think I might be pregnant and I have been on 150 mg of azathioprine a day for several months now.  I worry because it is a pregnancy category D.  So if any of you had azathioprine babies, were they ok?  Also, if I'm not pregnant, We are hoping to get that way next summer and I'm wondering if  I need to wean off the azathioprine and how long I need to be off before trying to get pregnant.  Thanks.

Cookie's Wife
Regular Member


Date Joined Aug 2005
Total Posts : 299
   Posted 9/8/2008 7:24 AM (GMT -6)   
When I was on it I was told not to get pregant.  But I believe some woman on this site have had babies while on it (don't quote me :-) )
 
Hopefully someone who has had that experience will post soon and help you out a little more then me!
 
Good luck!
~april
 

 



mimik81
Regular Member


Date Joined Jan 2008
Total Posts : 88
   Posted 9/8/2008 7:41 AM (GMT -6)   
I was on 75 mg of Imuran when I was pregnant with my daughter. My GI and the fetal medicine unit at my ob/gyn both concluded that new research provided information that it is safe. Also, the risk of getting off of the meds and flaring up was much higher than staying on the medicine. My daughter was born just fine. She's a very healthy 2 year old.

Good luck!
Diagnosed with Crohn's for 13 Years
Currently on 75 mg Imuran

Tried prednisone, flagyl, pentasa, and Humira (developed drug-induced lupus and had to stop).


justjenjen
Veteran Member


Date Joined Nov 2003
Total Posts : 518
   Posted 9/8/2008 8:10 AM (GMT -6)   
Ditto what mimik81 said. Mine is now 7yrs. old. Very happy, healthy, beautiful, smart...the list is endless! :)

wibiff
Regular Member


Date Joined Feb 2008
Total Posts : 27
   Posted 9/8/2008 10:38 AM (GMT -6)   
Thanks for the posts. I took a pregnancy test this morning which was inconclusive, so I will try again in a few days. I am having mixed feelings, which I feel kind of guilty for. On the one hand, I hope I am not pregnant because it would not be planned and my daughter is only a year old next week. And I know it would be less stressful if I am able to get off the azathioprine before I get pregnant. On the other hand, I love being a mom so much, and I definately want more kids. My husband is stressed about putting my body through another pregnancy so I am kind of having to talk him into another child any way. So if I am pregnant, then I get another child for sure, but I would feel so guilty forever if something went wrong. Anyone else struggling with guilt feelings related to wanting to get pregnant despite some of the risks?

mimik81
Regular Member


Date Joined Jan 2008
Total Posts : 88
   Posted 9/8/2008 9:10 PM (GMT -6)   
I just have a 2 year old, and I do not want her to be an only child. I really wish my body would allow me to have several children, but I realize that this disease limits what we are physically capable of doing. I am going to wait another year...not because I don't want another baby, but this past year has been horrible. I now have drug-induced lupus from the Humira, and it is very painful and limiting on top of everything else. I want that to go away before I even think about another baby. I get mad sometimes that I have to be so careful about having children.... I get jealous that some people don't deal with these issues, but I guess it could always be worse. At least I was able to carry one child - that's more than some.
Diagnosed with Crohn's for 13 Years
Currently on 75 mg Imuran

Tried prednisone, flagyl, pentasa, and Humira (developed drug-induced lupus and had to stop).


Kaycie
Regular Member


Date Joined Jan 2006
Total Posts : 449
   Posted 9/9/2008 2:52 AM (GMT -6)   
I did not take Imuran while pg, but did take Remicade. My docs recently wanted to put me on Imuran and we are not done having children, so we sought a 2nd and 3rd opinion on the drug. Long story short, I'm not on Imuran, but it has NOTHING to do with the pregnancy issue. In fact, they have not found any greater birth defects with Imuran, so you should be fine.

Keep in mind, it is better for you and baby to stay on your current drug regimen. If you flare while pg, it can be harmful to both you and your baby. I would definitely get on a regular schedule with your GI. I saw mine every 6 weeks while pregnant just to ensure I had no problems.

I"m sure your little one will be fine, but I most certainly understand the anxiety involved!
Kaycie - Age: 26
Crohn's - Dx Nov 05
Remicade - Next infusion - July 10th - new dose - 10mg/kg
IVF #1 (In-Vitro Fertilization) - Failed
IVF #2 - IVIg, Heparin, Baby Aspirin - TWIN GIRLS!!!
Reagan Dawn - 8/2/07 - Lived 1 hour 27 minutes due to Cloaca, NOT affiliated with my Crohn's
Addison Maria - 8/2/07 - 11 months old


Beth
Regular Member


Date Joined Aug 2003
Total Posts : 303
   Posted 9/9/2008 10:57 AM (GMT -6)   
I was on 150 mg of Imuran for my entire 1st pregnancy - and I have a happy, healthy 3 year old who starts preschool today!

I was on Humira for baby #2 (I was on Imuran too at first but stopped taking it early in my 1st trimester because I was able to maintain remission with just Humira). She is a happy, healthy 4 month old who is doing her best to "help" me type this. :)
Beth
 
Dx in early 1999
Resection in June 2006
Currently on Humira
 

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