Had a visit to the doc yesterday and confirmed what I was afaraid of....the Humira is not do much of anything and I most likely have a partial obstruction of the small intestine.
Here is what he said....and I invite comments and opinions on this...PLEASE...
First he thinks I should switch to Remicade. In his opinion many folks who don't see results with Humira can still do well with Remicade and conversley those who don't do well with Remicade can do well with Humira...so he feels it is worth a try.
He is not concerned with the possibility that the Humira could have contributed to the partial blockage nor is he concerned that the Remicade could make it worse. In his opinion it will not go away on its own anyway, he feels certain that it will require surgery eventually and said if the remicade makes it worse it really only sped up the process but would not change the end result which is the need to remove it. He says we will need to do some tests...maybe a C scan to see the partial blockage...but he is pretty sure it is going to be due to either a twising bowel or scar tissue. (I have had three major incidents from this in the past 4 weeks)
I am supposed to keep taking the Humira until he sets up the infusion of the Remicade, but he does want me to switch from 2 shots every other week, to one shot every week ...He does feel I need to have any waiting period between treatment of the Humira and the Remicade.
MY CONCERNS......Is it okay to go directly from Humira to Remicade?
Is mixing recombinant DNA technology with the Biologic treatment a good idea? I am concerned that I messing about with my bodies building blocks to much and could really do some damage. Maybe create cancer issues.
How often do partial blockages clear themselves up? What other things should I be doing to reverse it?
My first inclination is just chuck it and go back on Tysabri...but my current doc is pretty much against it based on the risk and if I insist on it he will okay it but will not do the infusions...i will have to travel to gainesville, fl for them.
dx IBS 1999 UC 2000 CD 2001
Tested BIOGEN TYSABRI (gave me 2 years of remission)
tried Naltrexone Jan. 19, 2007 Stopped the Naltrexone July 28th...started Humira Aug 31st, 2007...current dose two shots every other week.
Crohns is currently active and has been since April of 2005
52 yrs old