I just found out that the FDA has ordered a black box warning on Enbrel, Remicade, Humira and Cimzia for histoplasmosis. I have been on Humira since January, Remicade for several years before that. I have COPD and have had an awful time breathing since I went to the Humira. Everyone has attributed my cough/breathing problem to the COPD, fever and fatige to the Chrohns. I feel like I have the flu all the time, especially after an injection. Dr. just ordered a chest xray for this afternoon. I just read that a chest xray is useless for diagnosis of histoplasmosis, as it will only tell if my lungs are inflamed...duh, we already know that they are...I have COPD. Frustrating!
Be aware of the black box warnings.