Humira=Prednisone??? Are you crapping me?

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Regular Member

Date Joined Apr 2007
Total Posts : 165
   Posted 9/21/2008 12:22 PM (GMT -6)   
So I think I have mentioned to everybody before that I am all of the sudden getting HUGE (baseball) welts on my belly when I give myself injections....
So...   My GI is having me take PREDNISONE and BENEDRYL before each injection!
I am so mad.   I HATE seriods...   I am starting to HATE Humira....     Can I just go off all my drugs?   I think it would probably make my Dr mad....   But I am mad too!
28 Yrs
Newly diagnosed with Crohns

Veteran Member

Date Joined Mar 2007
Total Posts : 4527
   Posted 9/21/2008 1:55 PM (GMT -6)   
Hi Maybe taking the pred. just before the Humira will be better then having to take them all the time. The benedryl will help probably to keep the swelling down . Hope things look better for you soon. lol gail
Hallarious woman over 50 ,CD ,IBS 27 years--resection,fistula's,obstructions,and still gail

Veteran Member

Date Joined Feb 2006
Total Posts : 842
   Posted 9/21/2008 2:12 PM (GMT -6)   
It sounds like he's premedicating you, similar to how many people have to do before Remicade infusions. The prednisone lowers the inflammatory response, and you don't have to wean or anything because it's just one dose. Too bad you're getting welts from the Humira shots though!
Crohn's Disease for two years and counting (diagnosed March 8th, 2006)
Failed medications: Prednisone, Imuran, Remicade, Humira
Starting Tysabri the week of 9/22/08

Veteran Member

Date Joined Dec 2007
Total Posts : 2113
   Posted 9/21/2008 5:49 PM (GMT -6)   
Sometimes you only need to premedicate for a while. After several injections you may be able to ask about using just the benedryl as a premed and then maybe even not using that. But it is just one or two doses of pred not an everyday thing so the side effects should be minimal.
Good luck.
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