Prednisone, good drug for what it does but horrible for it's side effects (at least for me). On and off this stuff for years and it scares the hell outa me. I would puff up like a balloon, swollen feet, legs, retaining fluid like crazy. Had to sleep (when i could) with my feet elevated so i could pee some of the retained fluid away. Also pred has given me, osteoporosis, cataract surgery for both eyes, a full set of dentures because no matter how much brushing a flossing i still lost all my own teeth. I have heard other horror stories about pred as well, fluid collecting around the heart etc..
I am not on it now and hopefully never again. I will be starting remicade very shortly and am hoping for great things, i have heard lots of good news about it from other users. It HAS to be better than pred.