I had pain (anal/rectal fistula) but not much over my typical pain levels. I did have a sustained low-grade fever before I was able to note the abscess from the outside. Once the fistula was drained the fever went away. They found mine because I found the abscess...
--40 year old female, dx as UC in '04 (1st symptoms in '03), switched to Crohn's in '05, 1 fistula, crohn's colitis, limited to large intestine
--rejected (reaction/didn't work): Asacol, AZA, 6-MP, MTX, Remicade, Humira, prednisone
--methylpred - finally off 6/15/08, tried Prochymal in Phase III study (can't wait til it's approved!)
--started Tysabri 3/21/08
--single mom to 10-yr-old girl