I am extremely reactive to all 5ASA meds, with UC. But officially they refuse to consider me allergic. If I take any of them, though, I get severe worsening of UC symptoms including severe cramps, liquid D, increased bleeding, and extreme pain. No rashes or anything. I have always been puzzled that the literature on these meds (sulfasalazyne, Asacol, Dipentum etc) all indicates an extremely low percentage, a few percent or less, who experience D or worsening symptoms from them, because it seems to me that the percentage I see on Forums, who feel it makes them worse (but often keep putting up with it on their doc's insistence) is much higher than 10%. However, most definitely do not react badly. It's the backbone of maintenance therapies, as very little is out there other than heavy hitters and natural meds for maintenance, so hopefully you'll be luckier than me.
Often someone can't tolerate one 5ASA drug at all and another works fine. I gave up on ever touching another after I was 0 for 3.
Pancolitis 20 years ago, full med-free remission 10 years,
Flaring or simmering on and off ever since
10 20 17.5 15 12.5 10 mg 8 7.5 20 mg pred, 100 mg Imuran
Probiotics (Primal Defense and others), TSO,
boswellia, fish oil, many vits/minerals
Lower-carb version of Specific Carb Diet (SCD)