anybody heard of Ustekinumab?

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Ladybugs
Regular Member


Date Joined Jan 2006
Total Posts : 158
   Posted 10/7/2008 12:56 PM (GMT -7)   
I saw my GI today and he's doing a drug trial for Ustekinumab starting in November.  I've never heard of it before.  I've done a wee bit of reasearch on the web and haven't found much about Ustekinumab and Crohn's. 
 
Have any of you all heard of it? thanks

gachrons
Veteran Member


Date Joined Mar 2007
Total Posts : 4527
   Posted 10/7/2008 1:36 PM (GMT -7)   
No what Country are you in? lol gail
Hallarious woman over 50 ,CD ,IBS 27 years--resection,fistula's,obstructions,and still alive.lol gail


CrohnieYogi
Regular Member


Date Joined Oct 2006
Total Posts : 367
   Posted 10/7/2008 8:11 PM (GMT -7)   
"Ustekinumab is a new, human monoclonal antibody in Phase 3 development by Centocor, Inc. for the treatment of moderate to severe plaque psoriasis, and is being investigated as an infrequently administered subcutaneous injection. Ustekinumab is a novel biologic therapy that targets interleukin 12 (IL-12) and interleukin 23 (IL-23), naturally occurring proteins that are important in regulating the immune system and that are also believed to play a role in immune-mediated inflammatory disorders."

The above quote is from the link Kasper posted. This is exciting becuase scientists/physicians are getting closer to figuring out how to test for getting the right therapy for the right patient. So that means a simple blood test may help in getting us the right meds and not having to find it by trail and error.

Kaycie
Regular Member


Date Joined Jan 2006
Total Posts : 449
   Posted 10/7/2008 8:17 PM (GMT -7)   
CrohnieYogi said...
. So that means a simple blood test may help in getting us the right meds and not having to find it by trail and error.


Isn't that a NOVEL concept! ;) I can't wait!!! I'm tired of being a guinea pig for the pharmaceutical companies!
Kaycie - Age: 26
Crohn's - Dx Nov 05
Failed Remicade, moving onto a Clinical Trial called ABT-874 - Tentative start date - 10/2/08 - 10/16/08  - Infusion, every 4 weeks.
IVF #1 (In-Vitro Fertilization) - Failed
IVF #2 - IVIg, Heparin, Baby Aspirin - TWIN GIRLS!!!
Reagan Dawn - 8/2/07 - Lived 1 hour 27 minutes due to Cloaca, NOT affiliated with my Crohn's
Addison Maria - 8/2/07 - 13 months old


randynoguts
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Date Joined Jan 2003
Total Posts : 6049
   Posted 10/7/2008 9:26 PM (GMT -7)   
isnt that near uzbekastan, or krygystan?
randynoguts 



     http://www.geocities.com/randynogutsweb/


ivy6
Elite Member


Date Joined Sep 2005
Total Posts : 10404
   Posted 10/8/2008 12:47 AM (GMT -7)   
LOL, they were my thoughts exactly, Randy! :-)

It sounds like a place Borat would live.
Co-Moderator Crohn's Forum.


Ladybugs
Regular Member


Date Joined Jan 2006
Total Posts : 158
   Posted 10/8/2008 8:45 AM (GMT -7)   
I know, crazy name for a drug, huh?

Thanks for the input, everyone. My doctor said he was really excited about it because the preliminary data is good and the saftey data is good. I'm not sure I'm going to participate in the study, but I'll certainly talk to my doctor more about it.

I'll let you know what i decide : ) thanks

Reef08
Regular Member


Date Joined Dec 2005
Total Posts : 267
   Posted 10/8/2008 10:09 AM (GMT -7)   
I think this drug could be more effective than the Anti-TNF's.  I've been following it for a while.  It's about to be approved for Psoriasis.  It's pretty much causing 100% clearing in patients with severe psoriasis for months.  They only have to get the drug about 4 times a year.  Some of them have been symptom free for a couple of years now.
 
Since researchers found that IL-23 is one of the genes involved in Crohn's, this could be a very effective drug.

Rider Fan
Veteran Member


Date Joined May 2008
Total Posts : 1445
   Posted 10/8/2008 10:57 AM (GMT -7)   
God let's hope so. It would be about time.
Dx'ed in 1999. No surgeries.

Current meds: 100 mg 6MP. Just finished prednisone taper. Udo's Choice Probiotics (30 billion).
 
Betaine, digestive enzymes, Candicin (oil of oregano capsules), Beta Sitosterol.


ivy6
Elite Member


Date Joined Sep 2005
Total Posts : 10404
   Posted 10/8/2008 2:24 PM (GMT -7)   
How much would it cost once it came on the market? Does anyone know?
Co-Moderator Crohn's Forum.

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