6-mp and pregnancy

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airila
New Member


Date Joined Nov 2007
Total Posts : 18
   Posted 11/17/2008 1:47 PM (GMT -7)   
I have been on 6-mp and asacol for about 8 years now and haven't had a flare since.  My recent colonoscopy revealed very, very minor inflamation... nothing that would cause me to be symptomatic.  My husband and I would like to start a family but I'm worried about the 6-mp.  The reserach I've read is very contradictory, some articles say it's perfectly fine, some say it's a big no no.  I'm also scarred that my Crohn's could act up if I go off the 6-mp while pregnant. 
 
Anyone have advise or stories to share with 6-mp and pregnancy??? 

Lucillemom
Regular Member


Date Joined Apr 2005
Total Posts : 183
   Posted 11/17/2008 2:25 PM (GMT -7)   
Hi! I just wanted to say congratulation on wanting a family it is so exciting to start. I am not on 6mp, but I am on Immuran similar drugs. I was on it the entire time of my preg. and did just fine. I believe it better to stay on meds then go off of them and risk a huge flair. Ask your GI doctor what, he thinks. My obgyn also agreed with my GI.





Hemi and Fissure surgery that developed 2 abcess deep in my left cheek, by my rectum...(oh how fun!) Medication: Asacol 12 pills a day, Immuran 200 mg, Welchol 4 pills a day for diarhea

Pregnant for my second baby that is due Nov. 1, 2007

Thank God for my adorable daughter, who makes me smile
<FONT color=red>everyday!


Lucillemom
Regular Member


Date Joined Apr 2005
Total Posts : 183
   Posted 11/17/2008 2:25 PM (GMT -7)   
Hi! I just wanted to say congratulation on wanting a family it is so exciting to start. I am not on 6mp, but I am on Immuran similar drugs. I was on it the entire time of my preg. and did just fine. I believe it better to stay on meds then go off of them and risk a huge flair. Ask your GI doctor what, he thinks. My obgyn also agreed with my GI.





Hemi and Fissure surgery that developed 2 abcess deep in my left cheek, by my rectum...(oh how fun!) Medication: Asacol 12 pills a day, Immuran 200 mg, Welchol 4 pills a day for diarhea

Pregnant for my second baby that is due Nov. 1, 2007

Thank God for my adorable daughter, who makes me smile
<FONT color=red>everyday!


inflamed
Veteran Member


Date Joined Nov 2005
Total Posts : 1340
   Posted 11/17/2008 4:17 PM (GMT -7)   
Hi there. I was on 6mp before I had my daughter. My GI said he'd prefer me to be off it before getting pregnant. I went off, then did blood work after a few months. Since the blood work was fine and I was feeling well we then went ahead without the 6mp. I stayed healthy the whole pregnancy. I only took pentasa throughout. Now I am totally medfree to nurse and still doing all right. Good luck and congrats on starting a family. It's the best. My daughter isn't 3 mos yet, and I'm already excited to try for #2.
Hoping to stay in remission after the birth of a healthy baby girl. On Pentasa during my pregnancy, but Ive gone rogue and med-free to nurse.


NewToCD
Regular Member


Date Joined Jul 2008
Total Posts : 57
   Posted 11/17/2008 4:46 PM (GMT -7)   
I cant tell you from personal experience - bur from conversations with my doctors (both Gi & OB) they seem to think that you are better off staying on the meds. Healthy Mommy makes a Healthy Baby!
You have to decide what is right for you as this is definitely a personal decision but there are plenty of perfectly healthy, happy 6MP babies out there!!

airila
New Member


Date Joined Nov 2007
Total Posts : 18
   Posted 11/18/2008 2:03 PM (GMT -7)   
Thanks for all your comments! If anyone else has a story to share, I'm all ears! What a decision this will be!

amyv
Regular Member


Date Joined Dec 2003
Total Posts : 52
   Posted 11/18/2008 2:23 PM (GMT -7)   
I have had two healthy, full-term pregnancies while on Imuran (6-MP) and Pentasa.  My disease was inactive before and during the pregnancies, but my GI said the risk of my disease becoming active was greater than the risk to the baby.  Most of the "scary" research regarding the risks is based on the drug being used for other diseases at higher dosages.  I agree it would best to be off meds, and I worried every day of my pregnancy about it, but I am happy with my decision.  I was not able to nurse either baby, though, but my two and a half year old son and three-month old daughter both did fine with the formula.  I would be happy to answer any other questions you have.  Good luck! 

inflamed
Veteran Member


Date Joined Nov 2005
Total Posts : 1340
   Posted 11/18/2008 2:38 PM (GMT -7)   
Airilla, I didn't go off the 6mp soley for the preg either. I'd been on it for 5 years and was in remission, so we were thinking of doing just Pentasa anyway for maintenance. I agree with the others too, healthy mom = healthy baby. I'm off meds now to nurse, but if symptoms come back I'll be back on meds in an instant. My daughter needs me healthy to take care of her more than she needs to be breast fed. Good luck.
Hoping to stay in remission after the birth of a healthy baby girl. On Pentasa during my pregnancy, but Ive gone rogue and med-free to nurse.


SallyC
Regular Member


Date Joined Nov 2004
Total Posts : 158
   Posted 11/20/2008 1:12 PM (GMT -7)   
Hey!
I have been pregnant 4 times with my first being a first trimester miscarriage before I was diagnosed with crohns. The baby had trisomy 9 which is that something freakish happened when the chromosomes were dividing which is very common in first pregnancys for some reason. I didn't start the 6mp until I actually stopped nursing my second born son unfortunetly. I was in a mild to severe flare almost the whole year after having him and on asacol and steroids what seemed like the whole year too. When I became pregnant with the twins I did stop the 6mp in the first trimester (I am always way too anal in the first trimester due to my miscarriage which I still feel sad about today) but went back on it in the second trimester only to get really severe headaches for some reason. My doctor said to stop taking it and we would try it again after the babies were born. I was healthy through the pregnancy Thank God.

Anyways, I started taking it again when the twins were about 2 months old. (I did flare really bad about 5 days after they were born but started the steroids right away.) I still am nursing them at 13 months and my doctor, 2 different OBs one who has crohns herself, all my pediatricians and my lactation consultant do not see a problem with it. And I have to say that I feel my milk quality (quantity is the same) with the twins is and was way better because I have been so healthy compared to after having my second son. I happen to be someone who totally loves 6mp and have never felt so awesome since starting it.

I believe it to be safe but it is a personal choice. I have felt awesome while pregnant and always flare right after.
Good luck to you and as easy at is for me to say try not worry too much and enjoy trying. You and your doctors will guide you to the right decision when the time comes.

Sally
Sally
 
Diagnosed with UC in July of 2003 then diagnosed with Crohns in August of 2006.


Krica
Regular Member


Date Joined Apr 2007
Total Posts : 99
   Posted 11/20/2008 3:22 PM (GMT -7)   
Hi, i am pregnant 14 weeks and i am on 100mg imuran that is similar to 6pm, i am doing very well, crohn's is in remission. My doc tor did his thesis on imuran and pregnancy and he told me that it is safety to stay on the medication even in a high dose, there is a risk to come off the medication and have a bad flare up. It is very important you look after yourself before conception. I was on homeopath remedies over a year, which gave me positive results in relation to my crohn's and psoriase. Now i have a very balanced diet with lots of fruits and vegetables and i exercise three to four times a week (pilatos and yoga). Next week i will have an appointment with obs to discuss the possibility of change my medication, because i would like breastfeeding, imuran is toxic "no breastfeeding". I did a lot of research about imuran and pregnancy and many women here were in this drug while pregnant and had health babies. I had my first scan last week, my baby is doing very well, he is healty. I hope my post can help you to decide what is best for you and baby. Of course the best would be no medication at all, but in my case it was not possible , i have three strictures and one of them is very tight. If my crohn's flares could be a disaster. Thanks God everthing is perfect fine, i never been so health as i am now. My pregnancy is doing miracles. All the best, good luck in your decision.

dietcoke
Regular Member


Date Joined Jul 2008
Total Posts : 186
   Posted 11/21/2008 10:14 AM (GMT -7)   
Hi: I can't take 6mp because I am allergic to it. But, I did see Dr. Present once in NYC when I was doing really bad. Apparently he is the leading guy who headed all the 6mp research and clinical trials. Don't know much more than that but do know he is very well respected in the Crohn's arena. He basically said that being on 6mp was fine if you wanted to get pregnant and there were pictures of mothers and their babies all over his office who were on 6mp during their pregnancies. Just wanted to share that story. I know drugs and pregnancy are scary. Hope that helps.
39 years old female, Dx'd 2000 Crohn's Colitis in entire colon
Allergic to Asacol/Pentasa/6MP/Immuran and many others (too many to remember)
Past meds: Cipro, Pred
Current meds: Humira (...and waiting for it to work)


airila
New Member


Date Joined Nov 2007
Total Posts : 18
   Posted 11/21/2008 11:47 AM (GMT -7)   
Again, thank you everyone for your helpful feedback!
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