How quickly does Entocort and 6mp begin to work?

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Regular Member

Date Joined Jul 2004
Total Posts : 114
   Posted 11/21/2008 6:48 PM (GMT -6)   
Just started on 12mg of Entocort daily and wondered how fast others have responded to it. I'm also taking 75mg of 6mp daily. Also, I upped my dose of 6mp from 50mg to 75mg. How quickly does the extra amount start to work? Right now I have terrible bloating, gurgling, and pain if I eat any bread, cookies, etc. . .

Crohn's 2/02

Regular Member

Date Joined Nov 2008
Total Posts : 192
   Posted 11/21/2008 7:00 PM (GMT -6)   
I started feeling better after about a week of Entocort, but I just have a "medium" case of Crohn's right now (that's how my doc explained it). I read that Entocort starts working pretty quickly, so if after two weeks you are not feeling better, you should probably tell your doctor. Also, I am not on 6mp. I hope the meds work quickly for you too!

Regular Member

Date Joined Jul 2004
Total Posts : 114
   Posted 11/21/2008 7:10 PM (GMT -6)   
Thanks for your help catpower.

New Member

Date Joined Oct 2007
Total Posts : 9
   Posted 11/22/2008 9:23 AM (GMT -6)   
My experience with 6MP is that it is very slow to work.  Most of what I have read suggests that the 6MP may take between 3-8 months before a significant effect.  In my own personal case (75 mg of 6MP) it took from July until October until I felt any sig improvement (4 mos)
Hope this helps

Veteran Member

Date Joined Sep 2007
Total Posts : 565
   Posted 11/22/2008 12:56 PM (GMT -6)   
entocort did not work for me. but it's like kasper said, it's topical and i had scar tissue it couldn't penetrate. i found that prednisone, as evil as it is, did find me some with normal bowel movements. i have been on 6mp for over a year and looking to possibly upping my dose to 100mgs in the next few weeks (i only weigh just over 100 lbs.) the 6mp has helped me quite a bit. my pain is less frequent and not as acute. i am still having really bad 12+ bm days. lucky me, i am going for another scope on december 2nd and depending how my strictures and intestines look i may be talking to a surgeon.

my advice is give the 6mp some time. it was about 4-5 months before i started to notice i was improving. i was really frustrated in the beginning and thought the 6mp wasn't doing anything but then thought back to before i started taking it and said, yeah, it IS helping.

good luck to you and hope you are feeling better real soon!
.: stephanie :.
33 y/o female diagnosed 8/8/7 with crohn's of the terminal ileum w/ stricture/scarring
meddies: 6mp, percocet, trazodone, ativan, iron, calcium, folic acid & some other vits

Veteran Member

Date Joined Dec 2006
Total Posts : 559
   Posted 11/23/2008 4:47 AM (GMT -6)   
I've been on Entocort for about two weeks now, and it seems to be helping.

One question I do have about Entocort - how long can you stay on it? Some of the stuff I read online says you should only use it for 3 months, and that's it's not a long-term treatment. But I'm not sure, and I value any opinions from those more experienced with this drug.

best regards,
Crohn's since 1988
3 resections

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