Thanks for the replies! I have been on Imuran for almost 3 years now so I do tolerate that pretty well. I was taking Asacol as well, but lately it had been making an exit without being digested. (without being too graphic) So GI took me off of it and ouch, more cd symptoms. Hence the addition of Entocort. I started it today and I didn't feel any of the funky side effects that I get with Prednisone. However, it did seem to piss off the stricture in my ileo-cecal area. Weird intestinal and rectal spasms that caused leakage among other things. But after a while, even that got better. We shall see how it goes. My GI did say to do 9 mgs for 1 month, 6 mgs for 1 month, and finally 3 mgs for one month. I will see him again in March. I have been having wierd stabbing pains right at the bottom of my rib cage on the right side for about a year now so I mentioned it to him. He said he wasn't sure what that could be ("seems too high to be bowel and too far right to be gall bladder but lets just ultrasound it to be sure"). So next Friday I will have an abdominal ultrasound at 9 am and a thyroid ultrasound at 11 am (for a cyst on the half they didn't remove). Yippee fun! Anywho, he is also doing a specialized blood test to figure out the exact amount of Imuran actually circulating through my system to see if maybe I metabolize it too quickly. Hopefully, some of these tests will yield some kind of answer. And as far as the joint pain is concerned, I will take Ides' advice and see a rheumatologist in January. (I can't afford any more co-pays this month) Of course, this is providing I can tolerate the pain that much longer. I think this has been one of my worst symptoms as of late. SSooooo, I will keep you all posted on my progress. Have a great evening. And thanks for the advice, please keep it coming.