Crohn's or medications make us immunosuppressed?

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Jen77
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Date Joined Mar 2006
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   Posted 12/4/2008 2:21 PM (GMT -7)   
Unfortunately one of our pet bunnies came down with head tilt, which is caused by a parasite that apparently most are carriers of. Asked the vet if there was any worry about it being passed to us, and he said no, only in really severly immunosuppressed people. Like with AIDS. My husband wondered if that included myself. But I haven't been on prednisone since August, and the only Crohn's meds I take is Asacol. Never anything else, so I'd assume I'm okay there. Right? I know Crohn's alone is considered an auto-immune disorder, but that's because it's over reacting correct?
 
He kinda made me worry when we left there!
~Jennifer
 
Diagnosed with Crohn's Disease 2/06 after sever GI bleed. Has been suffering since 1998. History of rectal fistula and gallbladder removal. Taking Asacol, Questran, Toprol XL (for high blood pressure). Tapered off prednisone a month ago!


patientspiders
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Date Joined Jul 2005
Total Posts : 733
   Posted 12/4/2008 2:30 PM (GMT -7)   
I would use this as a perfectly legitimate excuse to delegate the cleaning of the bunny cage to someone who does NOT have crohn's, but for the most part - yeah - you're right. I don't think you would qualify as severely immuno-suppressed... maybe even the opposite, as I don't recall exactly which kind of med asacol is.

The only thing along these lines that my doc has ever vetoed was when I was working with raptors that had West Nile. He said it was too contagious to risk while I was on Remicade.
27f, dx'd CD July '05 after 6 fistula/abscess surgeries
(miscarried at 13 weeks, now waiting to heal before trying again)
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Jen77
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Date Joined Mar 2006
Total Posts : 2691
   Posted 12/4/2008 2:49 PM (GMT -7)   
Oh yeah, way ahead of you there on the cage cleaning! ;) Thankfully he's kept in our detached garage, so he's not in the house. But I did come in contact with him already (not knowing what was going on). I really wasn't concerned though until after what my husband said, made me question what I already thought I knew about being immuno-suppressed. I know if I were taking Remicade, or 6mp even it could be a more real problem. But I didn't think Asacol really fell in to those meds like that, hopefully!
~Jennifer
 
Diagnosed with Crohn's Disease 2/06 after sever GI bleed. Has been suffering since 1998. History of rectal fistula and gallbladder removal. Taking Asacol, Questran, Toprol XL (for high blood pressure). Tapered off prednisone a month ago!


CrohnsPatient
Regular Member


Date Joined Feb 2008
Total Posts : 314
   Posted 12/4/2008 3:37 PM (GMT -7)   
I think the REAL jury is still out on whether its over active or under-active immune-system. They actually have clinic trials BOOSTING the immune system that has shown some good results, which is exaclty backwards of our current therapies. So either way I think I'd just stay away.

Jen77
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Date Joined Mar 2006
Total Posts : 2691
   Posted 12/4/2008 4:19 PM (GMT -7)   
I have heard of that as well, very interesting since things like prednisone work so well, and it's weakening the immune system. Even if that is true, that it could use a boost, I sure wouldn't consider us severly compromised. Otherwise we would be seeing a lot of us, that are not on meds like Remicade, getting rare infections and the such.
~Jennifer
 
Diagnosed with Crohn's Disease 2/06 after sever GI bleed. Has been suffering since 1998. History of rectal fistula and gallbladder removal. Taking Asacol, Questran, Toprol XL (for high blood pressure). Tapered off prednisone a month ago!


ivy6
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Date Joined Sep 2005
Total Posts : 10404
   Posted 12/4/2008 6:57 PM (GMT -7)   
Of course, if you were very sick, very malnourished and very run-down, that would be another reason to be careful, no matter what meds you were on.
Co-Moderator Crohn's Forum.


Jen77
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Date Joined Mar 2006
Total Posts : 2691
   Posted 12/4/2008 7:08 PM (GMT -7)   
Oh absolutely. I've done quite a bit of reading on this today, seems quite rare for this to transmit to humans, and when it has it was those with AIDS mostly. They also are concerned about those that have had organ transplants and chemotherapy. So major stuff, but even then it seems rare. I will be taking precautions however, but I'm not that concerned. Right now *knock on wood* I'd actually consider myself quite healthy!
~Jennifer
 
Diagnosed with Crohn's Disease 2/06 after sever GI bleed. Has been suffering since 1998. History of rectal fistula and gallbladder removal. Taking Asacol, Questran, Toprol XL (for high blood pressure). Tapered off prednisone a month ago!


Osprey101
Regular Member


Date Joined Apr 2008
Total Posts : 227
   Posted 12/4/2008 9:46 PM (GMT -7)   
If your rabbit has the protzoal form of the disease, your vet probably suspects Encephalitozoon cuniculi. Google it up. I think the primary source of infection is urine, but I have no idea if rabbits shed the organism otherwise.

While prednisone may have a negative impact on your immune system (and it is dose-dependent, of course), the Asacol (mesalamine) is an anti-inflammatory and should not be cause for concern. TNF inhibitors, as has already been noted, would be a whole 'nother kettle of fish.

Good luck with your rabbit!
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