probiotics for persons with crohns disease

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New Member

Date Joined Nov 2008
Total Posts : 6
   Posted 12/23/2008 12:32 AM (GMT -6)   
Hi anyone out there tried probiotics for their crohns?
What was the affect, did they help out at all?
I would rather try something that won't mess my body up in other ways, like a lot of the meds they give crohns patients have a lot of adverse side affects.
Anything on probiotics would be helpful.
Thanks muchly.

Elite Member

Date Joined Feb 2004
Total Posts : 20552
   Posted 12/23/2008 12:44 AM (GMT -6)   
The therapeutic role of probiotics in the prevention of postoperative recurrence of Grohn's disease has been reported in some studies. Gampieri et al. (111) studied the effects of VSL3 in a randomized, investigator-blind trial. Forty patients with curative resection randomized within 1 week post surgery were divided into two groups of 20 patients. One group received mesalazine 4 g/day for 1 year and the other group received rifaximin 1.8 g/day for 3 months followed by VSL#3 6 g/day for 9 months. The endoscopic activity was assessed after 3 and 12 months. In the mesalazine group, eight patients had severe endoscopic recurrence after 3 months as well as after 12 months, whereas in the group with rifaximin and VSL3, two patients had a severe recurrence after 3 months and two patients after 12 months.

These results suggested the efficacy of the combination of a nonabsorbable antibiotic with a highly concentrated probiotic preparation in the prevention of severe endoscopic recurrence of Crohns disease after surgical resection.

In a pilot study Guandalini et al (112) investigated the possible effect of Lactobacillus GG in children with active Crohns disease. Four male patients with a median age of 14.5 years (range 10-18) were enrolled. In terms of clinical outcome, the patients showed significant improvement. In three patients receiving Lactobacillus GG, it was possible to taper the dose of steroids.

In a third published study using Lactobacillus GG this effect could not be confirmed. Forty-five patients were randomized to receive Lactobacillus GG 12 billion GFU/day (23 patients) or placebo (22 patients). A clinical remission after 52 weeks was seen in 15 of the 23 patients with Lactobacillus GG (83.3%) and in 17 of the 22 patients with placebo (89.4%).

Mild endoscopic activity was seen in nine of the 15 patients with remission in the Lactobacillus GG group (60%) and in six of the 17 patients with remission in the placebo group (35.3%). This study failed to show effectiveness in the postoperative prevention on Crohn's disease (113). More studies are therefore necessary. The limited experience indicates that different probiotics have different capacity to prevent intestinal inflammation.

Probiotics are becoming more recognized in the therapy aspect for IBD, there really are no side effects from probiotics, as they are simply friendly bacteria and IBDers tend to have bacterial over-growth of bad bacteria so probiotics are pretty much essential to aid with symptoms.

I use an excellent one called primadophilus reuteri made by natures way (feel free to google it for more info.).

My bum is broken....there's a big crack down the middle of it! LOL :)

Veteran Member

Date Joined Oct 2008
Total Posts : 1342
   Posted 12/23/2008 1:13 AM (GMT -6)   
I get my probiotics through homemade yogurt. There's supposed to be 3 billion cfu/mL of yogurt, and I eat a cup and a half a day, which is about a trillion cfu's. My intestines have felt happier since I started eating it (also doing SCD), and I'm no longer constipated. I'd recommend you give probiotics a try.

Elite Member

Date Joined Feb 2004
Total Posts : 20552
   Posted 12/23/2008 1:33 AM (GMT -6)   
I think for us IBDers it's also essential we take them daily and indefinitely (flaring or not) to help keep the balance in our gut flora...I also eat yogurt everyday as well as taking probiotic supplements, I just added eating yogurt everyday about a montha and a half ago now.

My bum is broken....there's a big crack down the middle of it! LOL :)

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted 12/23/2008 9:28 AM (GMT -6)   
Yes I believe all Crohnies should be taking probiotics daily. I take a Lactobacillus type. But taking a probiotic does not negate the need for maintainence type medications. JMHO
Been living with Crohn's Disease for 33 years.  Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, and Calcium.  Resections in 2002 and 2005.  Also diagnosed with Fibromyalgia and Osteoarthritis. Currently my Crohns is in remission.

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