Imuran (brand name) is notorious for making folks nauseous and gassy. Are you giving it to her with food? Another suggestion is to take it at bedtime with a light snack so you sleep thru the side effects. Imuran made me too nauseous, and I just couldn't tolerate it. Switched to its sister med 6mp and took it at bedtime and had no side effects except some hair shedding. But you can take Folic Acid with it to avoid the hair shedding. Maybe ask about switching to 6mp. Good luck!
Been living with Crohn's Disease for 33 years. Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, and Calcium. Resections in 2002 and 2005. Also diagnosed with Fibromyalgia and Osteoarthritis. Currently my Crohns is in remission.