disappointed with generic Colazal

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basil
Regular Member


Date Joined Oct 2008
Total Posts : 78
   Posted 1/4/2009 3:57 PM (GMT -7)   
This is mostly a vent. I was on the brand name Colazal for 2 months with great success. I decided to try the generic since the brand name was costing me more than $250 a month (I hate my insurance). After two weeks on the generic, pain and D returned. I suppose it could just be a flare and a coincidence, but I'm pretty sure the generic Colazal just isn't working for me. I'm hoping I can fight the insurance company on the cost of the brand name drug now that the generic isn't working. It would have been so much easier if the generic had just work. I really hate that these symptoms are back, I have felt so normal the last couple months.

Kaycie
Regular Member


Date Joined Jan 2006
Total Posts : 449
   Posted 1/4/2009 4:11 PM (GMT -7)   
You really believe the generic didn't work? It's supposed to be the same exact drug less all the marketing, advertising, and research.

Seems kind of odd to me, but enlighten me if I'm unaware of something...

Sorry to know it returned though. I know all too well the pain of the cost of Colozal...was on it for several months..and yes, mine (along with Rowasa) was nearly $300/month total...higher then my car payment
Kaycie - Age: 26
Crohn's - Dx Nov 05
Failed Remicade, moving onto a Clinical Trial called ABT-874 - Tentative start date - 10/2/08 - 10/16/08  - Infusion, every 4 weeks.
IVF #1 (In-Vitro Fertilization) - Failed
IVF #2 - IVIg, Heparin, Baby Aspirin - TWIN GIRLS!!!
Reagan Dawn - 8/2/07 - Lived 1 hour 27 minutes due to Cloaca, NOT affiliated with my Crohn's
Addison Maria - 8/2/07 - 13 months old


basil
Regular Member


Date Joined Oct 2008
Total Posts : 78
   Posted 1/4/2009 5:01 PM (GMT -7)   
My doctor told me that even though it is the same drug, it doesn't always work the same for people. I believe he said it has something to do with the delivery (I could be wrong here)?? He told me to keep me eye out around the 2nd or 3rd week of using the generic as that is when I may notice a difference. Sure enough, that's when my symptoms started to return.
I guess I'll have a better idea of what caused my symptoms to return when I try the name brand stuff again.

Kaycie
Regular Member


Date Joined Jan 2006
Total Posts : 449
   Posted 1/4/2009 8:11 PM (GMT -7)   
I'm so sorry! I'm sure it's possible. I take a lot of generics as I get them for a mere $5. But, I guess some of the Crohnie drugs are like that. Is there any chance he can try a different drug for you? I know in the beginning Colozal DID work for me (though, I progressed so quickly that it didn't last long - I progressed and then regressed within a 2 week period).

KUP. I hope you are on the mend soon... generic Colozal must be fairly new? I know my Rowasa I used to take just went to generic last year, and I was on Colozal just 3 years ago...
Kaycie - Age: 26
Crohn's - Dx Nov 05
Failed Remicade, moving onto a Clinical Trial called ABT-874 - Tentative start date - 10/2/08 - 10/16/08  - Infusion, every 4 weeks.
IVF #1 (In-Vitro Fertilization) - Failed
IVF #2 - IVIg, Heparin, Baby Aspirin - TWIN GIRLS!!!
Reagan Dawn - 8/2/07 - Lived 1 hour 27 minutes due to Cloaca, NOT affiliated with my Crohn's
Addison Maria - 8/2/07 - 13 months old


CrazyHarry
Veteran Member


Date Joined Mar 2006
Total Posts : 1034
   Posted 1/4/2009 10:33 PM (GMT -7)   
i was on colazal for years. i never felt it did anything for me. i was on pentasa and asacol, both for several years before my GI put me on colazal. the delivery is the same for these drugs as they are in the same family. the only difference is the manufacturer and the fillers. same active ingredient and thus it works the same way.

interestingly enough, i went to a CCFA sponsored seminar in san diego last year. the docs there said that crohn's patients respond no better to sulpha drugs (5-asa) than a placebo. made sense to me cos i was on virtually all of them, even rowasa enemas and cortifoam, all to no avail. conversely though, the research data does show that these drugs do help UC. how odd... anyhoo, talk to your doc about this. he must be aware of this as mine was when i approached him about it. the reasoning is that it just might help some of us (some people swear by asacol et. al.) and there is scientific evidence of the placebo effect. so dont be too mad with him (or her). but if you feel it aint working, my advice would be to save your money.
Crazy Harry

---------------------------------------------
Crohn's since 1993 (17 yrs old then)
surgery in July '05 - removal of 2 inches at ileum and 8 inches of sigmoid colon (had fistula into bladder)
Nov '05 developed colonic inertia; July '06 told i needed ostomy surgery
began maker's diet in August '06 - now feeling the best ever with no symptoms of colonic inertia and i kept my colon
med free as of 10/31/07


Kittikatt
Regular Member


Date Joined Jul 2004
Total Posts : 422
   Posted 1/5/2009 11:03 AM (GMT -7)   
Hmmmm....this topic has piqued my curiosity.

I, too, was on Colazal for 4 years and was in remission during that time. But at some point in...2006? 2007? my insurance stopped covering Colazal because they came out with a generic for it. In mid-2006 I started feeling bad. By January 2007 I was in a full-blown flare for a straight 8 months until a round of Prednisone helped out.

I'm still on the generic but now I'm curious as to when I started the generic...because my GI didn't prescribe it to me. I just went one day to pick up my Colazal and the pharmacy gave me the generic version instead, citing that my insurance would no longer cover the Colazal because there was now a generic version of it. I'm starting to wonder if my flare-up didn't start when I began on the generic Colazal, Balsalazide (?)...got to look into that one. I've never thought of that.
Diagnosed in October, 2004 at age 32.
36/F/SC
Current Rx's: Colazal (generic), Nexium (generic), Ferrous Sulfate, Librax, One-A-Day multivitamin, Probiotic, Omega-3 Fish Oil, Vitamin D, Vitamin A, Calcium-Magnesium-Zinc, Cranberry pills, Chromium Picolinate
Secondary conditions: mouth ulcers, joint pain, swelling ankles, extreme fatigue
Previous/occasional Rx's: 20mg Prednisone taper, Flagyl, Levaquin
No surgeries to date


basil
Regular Member


Date Joined Oct 2008
Total Posts : 78
   Posted 1/5/2009 6:54 PM (GMT -7)   
Crazy Harry, that is interesting about the placebo effect with the 5ASA drugs... My GI actually isn't 100% sure that I have Crohn's and not UC so maybe that's why the Colazal seemed to help me. It's interesting you say that though, now I'm wondering if I didn't psych myself out when I made the switch to the generic after the dr. told me it may not work the same :)

Kittikat, I wonder if your pharmacy could look at their records and see when they started giving you the generic. It is strange that what is supposedly the same drug may not work the same... but if my doctor warned me about it, there must be some slight difference that effects some people. It's worth looking into. I'm hoping to go back on the brand name and see if my symptoms clear up. I'm also debating trying Asacol as that brand name is covered by my insurance.
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