I tested positive to exposure to TB (i.e. latent TB) back in '90. I took INH for a year because I never wanted to worry about
the disease surfacing. Not only would I then have active TB and have to treat it with more meds, but I would easy expose several people to the disease who would then have latent TB.
In hindsight, with all the Crohn's meds I've had to take, I absolutely made the right choice to treat it. The side effects of those meds can be scary, but the right doctor will monitor your body's response to the med and make sure you are safe. I had monthly blood tests...
I am still unable to enroll in many clinical trials due to this unfortunate situation, but at least I know that I am eligible to take the TNF and other immune suppressing meds.
I assume you've seen a pulmonary specialist. I would discuss your fears with both that doctor and your GI. You don't want active TB...
PS - do not allow a second PPD (skin test). It's a reaction to the proteins and will get worse with a second test. This is assuming you had the skin test. There is the Feron Gold which is a blood test. that can be duplicated if your doctor thinks it's necessary. From my experience, it's unlikely to have a false positive. But, it's treatable and not the end of the world, just scary. Oh yeah, my sister is going through this right now... Hang in there!
--40 year old female, dx as UC in '04 (1st symptoms in '03), switched to Crohn's in '05, 1 fistula, crohn's colitis, limited to large intestine --rejected (reaction/didn't work): Asacol, AZA, 6-MP, MTX, Remicade, Humira, prednisone