Changing from Pentasa to Asacol...?

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ragbag
Regular Member


Date Joined Sep 2003
Total Posts : 109
   Posted 1/19/2009 2:45 PM (GMT -7)   
I was diagnosed with Crohn's about 12 years ago.  Suddenly my Pentasa is on the list of non preferred medications as I was so surprised to hear when I went to pick up my renewal prescription and instead of $40 it was to be $353.00!  So after being on this medication for 12 years now my gastro dr. must prescribe something else, although I have done wonderfully on Pentasa.  The patient coordinator said she may prescribe Asacol.  I'm naturally concerned about changing medications when I've done so well...feel like I could really be upsetting the apple cart here and wow, I don't like reading those possible side effects.  Are many of you on Asacol and have you had good or bad results on this ?  I would appreciate any info you can give me. 

Post Edited (ragbag) : 1/19/2009 3:07:12 PM (GMT-7)


LMills
Veteran Member


Date Joined Apr 2008
Total Posts : 1753
   Posted 1/19/2009 4:23 PM (GMT -7)   
I went from asacol to pentasa actually. They are the same thing basically except that pentasa is time released and meant to hit the ileum I believe whereas asacol does not have that. I'm sorry to hear that happened to you though...what a nuisance..
20 years old, Diagnosed with moderate to severe Crohn's and Colitis in May of 2008.
Currently taking:
Prednisone 15 mg, pentasa 2 pills 4x a day, bentyl as needed, omeprazole in the morning, multivitamin, humira every other week, and good probiotics.
Surgery for ectopic pregnancy most likely the result of severe Crohn's inflammation in July of 2008.
Attempting a diet without refined sugars, high fat content, bleached or bromated flour, most dairy, red meat, and avoiding anything spicy like the plague. Also refuse to eat anything with trans fat or high fructose/corn syrup.
"He who has a why to live for can bear with almost any how."


nitat
Regular Member


Date Joined Jan 2006
Total Posts : 79
   Posted 1/19/2009 4:50 PM (GMT -7)   
Ragbag,
I have had excellent results with Asacol. I have been on it for 10 years, although I have a mild
case of CD. I have not noticed any side effects, other than a slight backache when I first started
on it. Every case is different, so give it a try. Like LMills said, they are very close.

Ides
Forum Moderator


Date Joined Nov 2003
Total Posts : 7077
   Posted 1/19/2009 5:25 PM (GMT -7)   
Pentasa - Each 500 mg capsule contains 500 mg of mesalamine. It also contains the following
inactive ingredients: acetylated monoglyceride, castor oil, colloidal silicon dioxide, ethylcellulose, hydroxypropyl
methylcellulose, starch, stearic acid, sugar, talc, and white wax.

Asacol - Each Asacol delayed-release tablet for oral administration contains 400 mg of
mesalamine. Each tablet contains colloidal silicon dioxide, dibutyl phthalate, edible
black ink, iron oxide red, iron oxide yellow, lactose, magnesium stearate, methacrylic acid
copolymer B (Eudragit S), polyethylene glycol, povidone, sodium starch glycolate, and talc.
Moderator Crohn's Disease Forum
CD, Ankylosing Spondylitis, lupus, small fiber peripheral neuropathy, avascular necrosis, peripheral artery disease, degenerative disc disease, and a host of other medical problems.
 


ragbag
Regular Member


Date Joined Sep 2003
Total Posts : 109
   Posted 1/19/2009 5:58 PM (GMT -7)   
Thank you for your replies so far.  I do have CD in the ileum, so I hope the dr. knows what she's doing putting me on Asacol if it doesn't target that area...?  Isn't Asacol usually prescribed for Colitis or Ulcerative Colitis rather than Crohn's?  I guess all I can do is give it a try, or include Pentasa in the monthly budget.  Ugghhh.  Very frustrating.

Post Edited (ragbag) : 1/19/2009 6:11:30 PM (GMT-7)


LMills
Veteran Member


Date Joined Apr 2008
Total Posts : 1753
   Posted 1/19/2009 7:21 PM (GMT -7)   
I know that it's more common to prescribe asacol for Colitis and UC. One of my friends with UC takes asacol while I take pentasa for moderate to severe Crohn's. But you never know, it may work even better :) I had to be a lot more careful with my diet when I was on asacol(though failed with the coming of stress..) and, ironically enough, am even more so with pentasa. I started spending more for higher quality foods as well as those adhering(sort of) to certain diets like the SCD and am on less medicine now. I stopped taking alinia, mostly the bentyl, and am on a far lower dose of prednisone so...
Let us know how the asacol works for you!
20 years old, Diagnosed with moderate to severe Crohn's and Colitis in May of 2008.
Currently taking:
Prednisone 15 mg, pentasa 2 pills 4x a day, bentyl as needed, omeprazole in the morning, multivitamin, humira every other week, and good probiotics.
Surgery for ectopic pregnancy most likely the result of severe Crohn's inflammation in July of 2008.
Attempting a diet without refined sugars, high fat content, bleached or bromated flour, most dairy, red meat, and avoiding anything spicy like the plague. Also refuse to eat anything with trans fat or high fructose/corn syrup.
"He who has a why to live for can bear with almost any how."


73monte
Veteran Member


Date Joined Mar 2007
Total Posts : 1499
   Posted 1/19/2009 7:45 PM (GMT -7)   

Hi Ragbag,

Would you mind elaborating on the condition of your Crohn's? I've never heard from anyone yet that considered themselves mild. Have you had any complications or bad times in the last 12 yrs? I'm still holding out that my daughter could possibly keep her symptoms controlled or in a somewhat mild state. 

Thanks, Tom.


My daughter was diagnosed Feb. 19/07, (13 yrs. old at time of diagnosis), with Crohn's of the Terminal Illium. Initially, 9 weeks of Prednisone, currently taking 2000mgs of Pentasa.


Irishmom4
Regular Member


Date Joined Sep 2008
Total Posts : 457
   Posted 1/19/2009 8:29 PM (GMT -7)   
My GI told me that basically I could take either drug. I didn't notice a difference when switching. Hopefully the Pentasa will work as well as the Asacol. Best Wishes.

Elizabeth
dx'd with Crohns 1984, I was in remission for 12 years
Bowel Resection surgery 2006, Now on Pred. 20, and off Pentesa and Asacol to see how it goes


ragbag
Regular Member


Date Joined Sep 2003
Total Posts : 109
   Posted 1/19/2009 8:30 PM (GMT -7)   
Hi, 73monte.  I probably had Crohn's for 20 years before I was properly diagnosed.  I remember in the 1970s being told that I had inflammation of the intestines...well, that's what Crohn's is, but I was only ever given temporary medication fixits and had never heard of Crohn's.  I ended up in the e.r. 12 years ago in severe pain and vomiting and after many tests they said I had Crohn's Disease at the age of 45.  They put me on short term predinose and started me on Pentasa and I've of course had some bad days, but mostly good.  Nothing like many people suffer with.  I've had one severe flare, about 3 years ago I ended up in the hospital for 4 days.  I was running a very high fever because of the inflammation and at that time I was put on endocort for a time until I felt better. I am very careful to not eat foods that will irritate me at all, try to exercise.  Enough sleep is so important, easier said than done.  I feel well most of the time, and Pentasa seems to keep me feeling that way.  So rightfully so, I'm upset about this medication change because in a way it's like starting all over again.  I hope that your daughter does well.  It's an adjustment and requires some changes and some getting used to and being aware of our symptoms and enjoying all of our good days, especially after having a few not so good days, and they're going to pop up now and then.  This board has been very helpful to me...do you and your daughter belong to any support groups in your area?  I wasn't able to, but it would have really been nice to speak with someone who was going through the same thing.  There is absolutely hope that your daughter's medications will be helpful and that she can help herself to have those ''best days ever''.  The library has lots of helpful books too. There are some symptoms that are weird connected to Crohn's that one wouldn't imagine, but most I have much of the time, like joint pain or canker sores, fatigue, skin rashes, it all seems pretty mysterious, but easier to recognize through some reading.

Post Edited (ragbag) : 1/19/2009 8:59:45 PM (GMT-7)


73monte
Veteran Member


Date Joined Mar 2007
Total Posts : 1499
   Posted 1/19/2009 8:45 PM (GMT -7)   
Thanks so much for that prompt response. Sounds like you have things pretty much under control. I really doubt that my daughter will be able to stay on just Penatasa as a maintenance drug, as she's already having complications after only 2 yrs. I was really hoping that the Pentasa would be all she needed, but likely not the case. It's encouraging to know that there are some out there that can live a somewhat normal life with this disease. I'm still hoping and praying for that. 
 
Tom.
My daughter was diagnosed Feb. 19/07, (13 yrs. old at time of diagnosis), with Crohn's of the Terminal Illium. Initially, 9 weeks of Prednisone, currently taking 2000mgs of Pentasa.


ragbag
Regular Member


Date Joined Sep 2003
Total Posts : 109
   Posted 1/19/2009 9:06 PM (GMT -7)   

Tom, 

I am so sorry that your daughter is having such a difficult time. I will keep her in my prayers.

Ragbag


Wolfie40
Veteran Member


Date Joined Dec 2008
Total Posts : 947
   Posted 1/20/2009 4:40 AM (GMT -7)   
I've been on Asacol for 8 years now and I have not had any problems with it at all. I have CD in the TI and i ws on Pentasa when first diagnosed but I switched doctors and he highly recomended Asacol.
Insurance companies are weird, Penatasa will be cheaper compared to Asacol with my insurance.

No worries with Asacol
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