How long does it take...

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Veteran Member

Date Joined May 2007
Total Posts : 1488
   Posted 1/19/2009 4:53 PM (GMT -6)   
for Humira and/or Imuran to leave the body once you stop taking it?
I'm up for the dental surgery soon and I thought I'd ask the dentist my all time favorite long to heal after surgery too.
I haven't stopped any of my meds before so I'm kinda freaked out waiting for the flare to hit compliments of no meds and antibiotics.  I'm also raising the anti for recovery by increasing the probiotics too....which in turn makes a wonderful gas factory of and in itself.
Thanks for all responses cause if I don't get snowed in tomorrow I go for the dental consult to figure out what to do with what is left of the good teeth.

Veteran Member

Date Joined May 2007
Total Posts : 1220
   Posted 1/19/2009 5:18 PM (GMT -6)   
Hi Broomhilda,

When I had an allergic reaction to Humira, my doctor called Abbott. They said Humira stays in your body for 10 - 20 days. My reaction stopped on day 14. I don't know about Imuran. Hope your surgery goes very smoothly!
Diagnosed early 2007 with rectal Crohn's.  Several peri-rectal abscesses and two fistulas with setons.  Allergic to Remicade and Humira.  Currently on 6MP.

Forum Moderator

Date Joined Nov 2003
Total Posts : 7055
   Posted 1/19/2009 7:19 PM (GMT -6)   
Imuran metabolizes in the body to 6MP. The half-life of the metabolized 6MP is 3 hours [longer when one has renal disease]. So the last dose of Imuran you took would be out of your body in 24 hours or less. HOWEVER, the effect of the Imuran on the body like lowering of white count, pancreas effect, anemia, hair loss, etc, is going to be longer. I know when my white count fell too low on Imuran, it took about 10 days for it to get back to normal. I hope this helps.
Moderator Crohn's Disease Forum
CD, Ankylosing Spondylitis, lupus, small fiber peripheral neuropathy, avascular necrosis, peripheral artery disease, degenerative disc disease, and a host of other medical problems.

Veteran Member

Date Joined May 2007
Total Posts : 1488
   Posted 1/19/2009 8:12 PM (GMT -6)   
Thanks Fall Colors & Ides-that helps a whole lot! I should be good to go for surgery. Makes alot of sense that in only take 24hrs to rid the body of Imuran, however, it takes 4 months for it to "really" begin working doesn't it!
Dx'd Jan'06, 1st Resection 7/06, Humira, Imuran, B12 injections, Nexium, Lexapro, Nulev, Glucosamine, Multi-Vitamin, Calcium Citrate, Ultracet. Secondary conditions: Psorasis, Osteoarthritis, Fibromyalgia, Lactose Intolerant, gallstones, kidney stones & peri-menopausal.

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