I had 10 600 ml Remicade infusions at 4 weeks apart. On my last, I was not medicated and I developed severe back pains about half way through. They immediately stopped the infusion and changed the IV to saline, squeezing the bag to get it in faster to dilute the Remicade. The Dr. then saw me and ordered a Benadryl and steroid shot and they hooked me back up and finished the infusion without further complications. Usually Remicade does so much good (plus it is expensive), they will try to get it all in unless they think it is promoting a heart attack. I felt that my lack of pre-meds caused my reaction and felt I could keep having them thereafter. The Dr refused saying reactions tend to get worse so no more Remicad for me and probably for you. Currently I'm trying to get by on Immuran but my G.I. wants me to go on Humira.
Hope this helps.