Humira and Weight Gain

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Crohnie_Mel
Regular Member


Date Joined Jan 2009
Total Posts : 23
   Posted 1/28/2009 9:15 AM (GMT -7)   
Hello all! I am very new to this site but have read a bunch of posts and felt immediately comfortable so I thought I would post blush

I recently began Humira after being on almost every other drug out there...every pill known to man, prednisone (a nightmare!), remicade (which worked for some time but then stopped) and shortly after tried a Gluten Free diet with acupuncture (helped for a bit then stopped working yet again). Anyway, since this is also a TNF blocker like remicade i am a little skeptical however, it has been working. It's been working a little too well in fact....since I began taking the Humira I have become incredibly constipated and have felt that I'm putting on weight. My doctor says that an improvement, which it is but is it normal? Any tips? Thank you!!!

BeaWalsh
New Member


Date Joined Jan 2009
Total Posts : 3
   Posted 1/28/2009 10:28 AM (GMT -7)   
I am on humira too. I started it about 8 months ago and I found it very hard to loose weight and I was constipated as well. Which was very different for a change. I might check with my doctor too about this.

Jessica28
Regular Member


Date Joined Jan 2009
Total Posts : 21
   Posted 1/28/2009 2:19 PM (GMT -7)   
when i was on pentasa, i went to the bathroom at least three times a day. now i'm lucky to go once, which still isnt' bad though. my appetite is defintley back in full swing too!
Jessica
 
28 years old, diagnosed with Crohn's  in March, 2007.  Currently taking Humira 2 X month


firecracker1
Regular Member


Date Joined Apr 2007
Total Posts : 208
   Posted 1/28/2009 3:30 PM (GMT -7)   

I gained 40 lbs while on Humira. I went from a size 6 to a size 12 in 6 months. I had more energy, was a little constipated, but in general felt much better. I did not change my diet (I eat a low calorie, oganic diet) and I work out 45 min a day, 5 days a week.   

I had to stop taking it because insurance changed and it no longer covers it. However, while on Humira, I started getting chest pains, bad headaches, and fluid retention. My dr said not to worry about these side effects. That I was fine. I called the nurse hotline for Humira and they told me I needed to get my heart checked because those were symptoms of heart disease, which Humira can cause. The symptoms are right on the pamplet: rapid, unexplained weight gain; chest pain, fluid retention. They told me to check my blood pressure. It was really high. I am 37 years old and have never ever had high blood pressure. I am always seeing doctors and have not had high blood pressure until now. Now I am on blood pressure medicine and am still struggling to lose the last 20 lbs. I just had an echo cardiogram and stress test yesterday. It will take 48 hrs to get the results. This medicine is new and weight gain is caused in some, but not all. However, I am not sure if it is a serious side effect (indicating heart problems) or if it is just something that happens in some, not all who take it. 

This medicine is a godsend for some, and can cause bigger issues for others.


Curly9878
Regular Member


Date Joined Apr 2007
Total Posts : 165
   Posted 1/28/2009 5:40 PM (GMT -7)   

I also gained 40 lbs on Humira....    Not to mention I was exhausted the whole time I was on it.

Woah, my name is also Mel...   Did we just become best friends?


28 Yrs
Michigan
Newly diagnosed with Crohns


Ides
Forum Moderator


Date Joined Nov 2003
Total Posts : 7077
   Posted 1/28/2009 6:04 PM (GMT -7)   

Remicade is known to cause unexplained weight gain in patients [ http://www.medpagetoday.com/MeetingCoverage/ACG/6976 ]

I also read a report citing the same thing happening with the other anti-TNF agents. However, I can't find my link to that article right at the moment.


Moderator Crohn's Disease Forum
CD, Ankylosing Spondylitis, lupus, small fiber peripheral neuropathy, avascular necrosis, peripheral artery disease, degenerative disc disease, and a host of other medical problems.
 


Crohnie_Mel
Regular Member


Date Joined Jan 2009
Total Posts : 23
   Posted 1/29/2009 8:25 AM (GMT -7)   
Woah....thank you for all the replies...however now I am getting nervous! I totally grew "lovehandles" overnight --- my doctor said that I am starting to take in the full content of the food i am eating so that could be why. I am just kind of overly aware of my body now since all these other medications either gave me horrendous side effects or didn't work. How long were you on Humira? Did any other side effects develop? Firecracker I am sorry you had to go through that and hope you are feelings better! And Mel -- best friends for life lol smurf

snappy
Veteran Member


Date Joined Sep 2005
Total Posts : 675
   Posted 1/29/2009 1:48 PM (GMT -7)   

Hello,

 

I'm another weight gainer. I was at 165 for about 15 years, the was dx with crohns and lost 25 pounds. After getting Remicade I gaind back to norma, and kept going! I now weigh 187. I am a healthy eater (no fast food) and exercise about one hour daily. My doc said the same thing; that I am now absorbing food that I wasn't absorbing before. I don't believe that. I spent all those years at 165 feeling great, running 21 marathons. How would I have the energy for that if I wasn't absorbing my food back then? I've made attempts at losing weight such as cutting out all bred and pasta and cutting portion sizes but I'm up a pound or two almost every time I go to the doc (every 8 weeks). I'm not worried, but really, someone should admit that TNF blockers cause weight gain.

 

Ted


Bad fissure Feb 2005, still have it January 2006. On Pentasa and Imuran 100mg. Some slight swelling and ulceration of terminal ileum. No other symptoms. Now on Remicade!


MaggieLou
Regular Member


Date Joined Apr 2008
Total Posts : 31
   Posted 1/29/2009 2:58 PM (GMT -7)   
Here's another weight gainer.  I have gained about 20 lbs. since strating Humira in 04/07.  But the weight is worth it.  Unlike some, I still spend a lot of time in the bathroom - 5 to 10 times a day, but the pain is much better.
 
Susie
 
Susie
CD since 1972 (three bowel resections), Fibromyalgia, Inflamatory Arthritis, Degenerative Disc Disease, High Blood Pressure, Depression, Acid Reflux
Humira since 04/07 for CD, Prozac, Diovan, Cardizem, B12 Inj., Prevacid, and Lortab and Ambien as needed for Fibro
 


Curly9878
Regular Member


Date Joined Apr 2007
Total Posts : 165
   Posted 1/31/2009 4:09 PM (GMT -7)   
Mel... No worries, fat is where its at!
28 Yrs
Michigan
Newly diagnosed with Crohns

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