I have had crohns for 20 years, 1 resection with ostomy, i got toxicmegacolon after surgery therefore needed an ostomy. After all those problem, I went 10 years in remission without any medications...it was great. But it showed it's ugly head again, and this last year I had an abcess in my rectum, had that removed, not a big deal and then got a fissure with a sentinel pile. Had surgery for that...not too bad either. The doctors put me on Imuran 150 mg, Predisone with varies sometimes 5 mg to 20 mg. I am still have attacks, but mostly tired all the time so bad I can't get to work. Seems to be sick every 2 weeks. I can't go on like this. Wondering about Remicade and your experiences with them and I think that maybe my next step. What are the side effects of Remicade? On a good note i went to the acupuncturist this evening and it did really help.