Rather Fascinating Tale of Near Extinction & Re-Birth of Crohn's Linked Gene

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CrohnieToo
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Date Joined May 2003
Total Posts : 9448
   Posted 3/6/2009 10:46 AM (GMT -7)   
This story is quite interesting. At least I thought so.
 
http://www.nature.com/news/2009/090305/full/news.2009.140.html
Some people are like Slinkies... Not really good for anything, but they still bring a smile to your face when you push them down a flight of stairs.


LMills
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Date Joined Apr 2008
Total Posts : 1753
   Posted 3/6/2009 10:53 AM (GMT -7)   
Oh wow...that is pretty interesting. Thank you for posting!
It's a lot to think about in light of new research able to reshape proteins which could in turn cause other genes to copy the correct shape and code. Potential cure perhaps?
20 years old, Diagnosed with moderate to severe Crohn's and Colitis in May of 2008.
Currently taking:
Prednisone 5 mg, pentasa 2 pills 4x a day, bentyl as needed, omeprazole in the morning, prenatal multivitamin, humira every other week, and good probiotics.
Surgery for ectopic pregnancy most likely the result of severe Crohn's inflammation in July of 2008.
Attempting a diet without refined sugars, high fat content, bleached or bromated flour, most dairy, red meat, and avoiding anything spicy like the plague. Also refuse to eat anything with trans fat or high fructose/corn syrup.
"He who has a why to live for can bear with almost any how."


pb4
Elite Member


Date Joined Feb 2004
Total Posts : 20576
   Posted 3/6/2009 11:50 AM (GMT -7)   
Well, to me that just proves that crohn's is a hereditary/genetic disease for all crohnies not just a percentage.

Thanks for posting that interesting article C2, nice to see you again :)
My bum is broken....there's a big crack down the middle of it! LOL :)


Sniper
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Date Joined Feb 2004
Total Posts : 6518
   Posted 3/6/2009 1:16 PM (GMT -7)   
It would not have bothered me if it had gone extinct..
If we would read the secret history of our enemies,we would find in each mans life sorrow and suffering enough to disarm all hostility.


LMills
Veteran Member


Date Joined Apr 2008
Total Posts : 1753
   Posted 3/6/2009 2:58 PM (GMT -7)   
As much as it's increasing though I wonder how it can be solely genetic...I think that there are a lot of environmental factors at work.
20 years old, Diagnosed with moderate to severe Crohn's and Colitis in May of 2008.
Currently taking:
Prednisone 5 mg, pentasa 2 pills 4x a day, bentyl as needed, omeprazole in the morning, prenatal multivitamin, humira every other week, and good probiotics.
Surgery for ectopic pregnancy most likely the result of severe Crohn's inflammation in July of 2008.
Attempting a diet without refined sugars, high fat content, bleached or bromated flour, most dairy, red meat, and avoiding anything spicy like the plague. Also refuse to eat anything with trans fat or high fructose/corn syrup.
"He who has a why to live for can bear with almost any how."


pb4
Elite Member


Date Joined Feb 2004
Total Posts : 20576
   Posted 3/6/2009 3:29 PM (GMT -7)   
The environmental triggers are linked to those that are genetically predisposed to getting IBD, if you're predisposed but it doesn't get triggered in your life time then you're a very lucky IBDer and I'm sure it does happen, that's why I say to those who post that they are the only ones in their families that have it, there's no possible way anyone can know their entire family medical history for all past family members, great great great grandparents and the like.

:)
My bum is broken....there's a big crack down the middle of it! LOL :)


snohare
Veteran Member


Date Joined Oct 2004
Total Posts : 2088
   Posted 3/6/2009 5:13 PM (GMT -7)   
tongue I don't know which was better - the article, or the signature... the article will lend me focus to the Crohn's paradigm, but I often find the signature popping into my head when talking to people in everyday life ! yeah
You see, your very merest presence has a salutary effect upon us, C2. smilewinkgrin

LMills
Veteran Member


Date Joined Apr 2008
Total Posts : 1753
   Posted 3/6/2009 8:32 PM (GMT -7)   
While I agree with you pb4 I still don't think 100% of the cases are purely genetic...I feel like there are too many things that we're exposed to that we shouldn't be e.g. mercury, lead, etc. and I wonder sometimes if some people diagnosed with Crohn's are actually experiencing Crohn's or something very similar..
20 years old, Diagnosed with moderate to severe Crohn's and Colitis in May of 2008.
Currently taking:
Prednisone 5 mg, pentasa 2 pills 4x a day, bentyl as needed, omeprazole in the morning, prenatal multivitamin, humira every other week, and good probiotics.
Surgery for ectopic pregnancy most likely the result of severe Crohn's inflammation in July of 2008.
Attempting a diet without refined sugars, high fat content, bleached or bromated flour, most dairy, red meat, and avoiding anything spicy like the plague. Also refuse to eat anything with trans fat or high fructose/corn syrup.
"He who has a why to live for can bear with almost any how."


gachrons
Veteran Member


Date Joined Mar 2007
Total Posts : 4527
   Posted 3/7/2009 5:15 AM (GMT -7)   
Seems that deleting did not work and is a useless thought seeeing that it was able to stand the test of time ,now that there are so many other genes linked to crohn's makes me wander if they too were not available at one time..if there are so many other links to crohn's ,I would think that it may be unavoidable in the future of most... not to worry I guess I already have evidence of being part mouse now as I seem to nibble alot... certainly a interesting thought ..lol gail
Hallarious woman over 50 ,CD ,IBS 27 years--resection,fistula's,obstructions,hemmies,and still alive.lol gail

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