Julie, I took Cimzia for over a year on a clinical trial. Here is my experience:
1. I received injections as part of a clinical trial and had to stay there for 30 minutes afterwards as part of their regulations.
2. Dosage wasn't based on weight in the clinical trial. Everyone received the same amount. Not sure how it's done now that the drug is on the market, but I thought it was a standard dosage still.
3. I always received two injections at a time...I chose to have them in my legs, so one in each leg.
4. See #1. They stayed with me.
5. Cimzia worked better for me than Remicade did (I lost response to Remicade). Seems to work about the same as Humira.
6. I still premedicated because I got injection site reactions.
7. I was told I needed to wait one month in between the two.
Julie, the clinical trial I was on said that all of their participants saw a good response to it, so maybe it depends on who you ask...what their personal opinion about the drug is. As for why I'm not still on it, I had the option to continue it once the trial ended, but I was still having a little difficulty with my arthritis, so I decided to try Humira just to see if it worked any better (once you start feeling good, you notice the little aches more!). Also, on the trial, I was receiving Cimzia every 2 weeks, and I would feel worse a couple of days before my next injection was due. Once the drug was available on the market, it was only approved for monthly use and I was just afraid that I wouldn't be happy only getting it once a month...and who knows, maybe that's why some people aren't seeing as good of a response now, since people are only getting it once a month, vs. biweekly on the trial.
So, I am on Humira and I still have arthritis problems, but at least now I know that I can take another shot every 2 weeks, so it's a little easier to deal with the problem...knowing it won't last too much longer. But, there have been some bad flares lately that have made me seriously consider trying Cimzia again, so who knows where I will end up. Both drugs kept my Crohn's in remission, it's just the arthritis that won't give in. Good luck, I hope it works wonders for you. I know that I was very happy that year that I was on Cimzia, compared to Remicade...just thought maybe there were even better options out there.
Post Edited (Becoming undone) : 3/27/2009 5:19:43 PM (GMT-6)