pain killers not working

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Regular Member

Date Joined Jun 2008
Total Posts : 221
   Posted 3/28/2009 8:37 AM (GMT -6)   
I have been on a number of different pain killers in the year and half I've had crohns.  In the beginning they would work but after a while they would stop working. Now I can try a different pain killer and they dont work from the start.  I just had my second surgery in a week. 7th in all and the doctors keep giving me pain killers that aren't doing anything.  I have started to mix combinations of pain killers in the hopes that I will find something that does work. I know this is not a good idea but what else am i suppose to do.  I cant move otherwise.

Veteran Member

Date Joined Dec 2005
Total Posts : 1768
   Posted 3/28/2009 8:42 AM (GMT -6)   
Have you talked to your doctors about this? Maybe they would have a suggestion of what to do. It can be dangerous to mix drugs if you don't know if they go together. Be your doctors and try to get them to help you resolve this.

Sorry you're going through so much pain. I hope it gets better soon, and you find a solution.

31 yr old female-dx with Crohn's in '97 after emergency resection and appendectomy, 2nd resection '05
Currently on Humira, Prilosec, Effexor, Seroquel, Calcium, Vit D, sublingual B12; phenergan, ultram, clonazepam as needed

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted 3/28/2009 8:54 AM (GMT -6)   
Maybe you should ask for a referral to a pain mgmt doctor. Hope you get some relief soon.

Gail *Nanners*
Gail*Nanners* Co-Moderator for Anxiety/Panic Forum
Been living with Crohn's Disease for 33 years. Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, and Calcium and Xanax as needed. Resections in 2002 and 2005. Also diagnosed with Fibromyalgia and Osteoarthritis and Anxiety. Currently my Crohns is in remission.
*Every tomorrow has two handles.  We can take hold of it by the handle of anxiety, or by the handle of faith"*

Becoming undone
Veteran Member

Date Joined Jul 2007
Total Posts : 927
   Posted 3/28/2009 9:37 AM (GMT -6)   
I posted this article in the chronic pain forum...but it is applicable here too (especially here).
"Translational pain research: Evaluating analgesic effect in experimental visceral pain models" World J Gastroenterol 2009 January 14; 15(2): 177-181
If you look at the date, this article is very recent . Also they are finding (and it has been shown for quite some time) that visceral pain must and needs to be treated differently. However, given many docs lack of knowledge in the areas of pain relief (beyond the very basics), and to be fair, the wealth and depth of knowledge they have for other minutia, visceral pain is often treated the same way as musculoskeletal pain (if you look there are many article and books even...Peer reviewed, about these differences)...
"The earth laughs in flowers"

Veteran Member

Date Joined Jan 2006
Total Posts : 768
   Posted 3/28/2009 1:10 PM (GMT -6)   
Hpe you get the right combo,but I think you should ask Doc about which go together. Mixing meds can be a recipe for bigger problems. I keep trying to tell myself pain means I'm still alive. Sometimes it works, sometimes I am the biggest liar on the planet!
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