DEFINITELY. I've had periods like that several times...particularly prior to being diagnosed. Last year when I was in a flare, I dealt with loss of appetite. NOTHING appealed to me...not even pizza!
This year's flare, which I've been in bad since January, has really taken a toll on me as far as loss of appetite and not eating. Sometimes when we're in pain, fatigued and spending the day either in the bathroom or the bed, it's hard to get yourself up to even bother fixing something to eat...or just to go grab an Ensure out of the frig. I really struggled with that.
I went too long at the first of this year not getting nearly enough calories in my system and I paid for it dearly. I dropped close to 10 pounds within the month and could barely hold my head up or think straight. I was starving myself but couldn't feel it. Luckily I have a mom who is supportive and was willing to stay with me for as long as it took to gain my strength back from malnutrition and dehydration. She's fixed all my low-residue meals and helped remind me to drink my Ensure etc...it's been almost a month but I'm feeling better.
But loss of appetite for me comes and goes depending on what my Crohn's is doing to me on any given day.
Diagnosed in October, 2004 at age 32.
Current Rx's: Colazal (generic), Omeprazole, Ferrous Sulfate, Librax, One-A-Day multivitamin, Probiotic, Omega-3 Fish Oil, Vitamin D, Vitamin A, Calcium-Magnesium-Zinc, Cranberry pills
Secondary conditions: mouth ulcers, joint pain, swelling ankles, extreme fatigue
Previous/occasional Rx's: 20mg Prednisone taper, Flagyl, Levaquin
No surgeries to date