I started Cimzia about a month ago and just wanted to share my experience thus far. I was previously on remicade, which initially worked like a miracle but eventually wore off after about 1.5yrs. I was then put on Humira, which produced a very similar reaction and I was completely symptom free for another 1.5yrs. However, about 4 months ago the Humira also started to lose its effectiveness and I've been on a rapid decline ever since. After switching to a new doctor, and working with him for a few months, we decided to try Cimzia in hopes that I would have a similar experience to the other biologics that I have been on in the past (remicade/humira) Unfortunately, I haven't noticed much of a change... certainly not the complete reversal that I felt with remicade/humira. I am coming up on the 3rd and final loading dose next week and the doc says that he'll give me 2 weeks after that before considering this medication as "ineffective."
My next option will be 6-MP, another medication that I have not yet tried. Having seemingly become immune to the biologics, I'm hoping that the 6-MP will get me back to normal because it seems like I'm running out of options. In the past 4 months, I've dropped about 40lbs and I've been struggling just to get through each day. This week, I finally got to the point where I really couldn't stand the pain any longer and my doc reluctantly prescribed 40mg of Prednisone, which will hopefully hold me over until I can start the 6-MP. I will be tappering the pred 5mg every 5 days and I should be able to come off right about the time that I would be starting the 6-MP.
Anyway, I know there are a few others here that have started Cimzia recently and I would be interested to hear what kind of results you have seen. I hope those of you that are trying it for the first time have a bit more positive story to share.
24 M - Diagnosed with CD in 2005
Currently taking Humira and no other meds
Post Edited (Cincinnati27) : 4/3/2009 4:04:02 PM (GMT-6)