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goldy3
Regular Member


Date Joined Feb 2009
Total Posts : 139
   Posted 4/4/2009 12:38 PM (GMT -7)   
I tried imuran but had to get off b/c my liver functions became too high...does that mean I can't take 6mp since they are similiar?...has anyone had high liver functions with imuran and switched to 6mp?
42 year old woman diagnosed with UC 1991, Jpouch surgery 1992, Crohn's diagnosis 2009
Current meds: 500mg 2x's daily cipro, 800mg xifaxin, 9mg entocort, Humira (started 3/23/09), synthroid
 


goldy3
Regular Member


Date Joined Feb 2009
Total Posts : 139
   Posted 4/4/2009 1:38 PM (GMT -7)   
I thought I read some post were some people did well on one and not the other....

42 year old woman diagnosed with UC 1991, Jpouch surgery 1992, Crohn's diagnosis 2009
Current meds: 500mg 2x's daily cipro, 800mg xifaxin, 9mg entocort, Humira (started 3/23/09), synthroid
 


brit tuck
Regular Member


Date Joined Jun 2007
Total Posts : 143
   Posted 4/4/2009 5:40 PM (GMT -7)   
They typically do some bloodwork before you start either medication to determine which one would be better for your body. But it's not always 100% accurate. My results put me in a weird level (I wish I could remember the terms right now or help be more descriptive). So I started on 6-MP but it made me super nauseous. I just couldn't deal with it. My doctor had me switch to try Imuran because apparently a very small percentage of people who have trouble taking 6-MP can take Imuran. I've been having problems recently of being super exhausted, so I'm going off of Imuran for two weeks to determine if that's the cause of the problem. But I hadn't been having the nausea or anything like that on Imuran. Really it depends on your lab results and what the doctor will talk to you about. Wait and talk to your doctor and determine together (with additional research) what you think your next step should be. Good luck!

kimmy2
Regular Member


Date Joined Sep 2008
Total Posts : 91
   Posted 4/4/2009 6:08 PM (GMT -7)   
I got pancreatitis on 6mp after 2 years of taking it, and my dr. said I could not take Imuran either. He switched me to Methotrexate often used in Rheumatoid Arthritis as an immunosuppressant. I haven't had the problems with pancreas and it. I use a combination of Cimzia, Methotrexate, Folic Acid, and Omeperazole and am doing better than I have in 16 years with GI symptoms. I've developed Pyoderma Gangrenosum (skin condition with Crohn's) and it's been a whole new hell. Good luck to you.
diagnosed CD '03 after suffering for 10 yrs.
 
re-section surgery '05, Chronic Pancreas problems, joint and muscle issues (from Remicade), diagnosed March '09 pyoderma gangrenosum
 
meds been on-Asacol, Pentasa, Lialda, Remicade, Humira, 6-MP, Methotrexate, Rowasa, Prednisone, too many pain meds to list
 
Currently on-Cimzia, Cymbalta, Reglan, Pamine Forte, Methotrexate, Folic Acid, Probiotics, Phenergan, Omeperazole, and Klonopin(RLS) (IV Vancomycin, Fortaz, Solumedrol, and Lasix)


lenagirl
Regular Member


Date Joined Aug 2007
Total Posts : 44
   Posted 4/4/2009 11:14 PM (GMT -7)   
I just read a study somewhere recently that said actually about half of people who could not tolerate 6 MP did well on Imuran, so it could work the other way around too. I think it's at least worth discussing with your doctor.

pdmhol
Regular Member


Date Joined Apr 2007
Total Posts : 40
   Posted 4/7/2009 12:47 PM (GMT -7)   
I had a severe reaction to Imuran but took 6 mp for 2 years untill my Gi switched me to Humira last december.
Crohns dx in 2002. ilieum and colon resection 2002. Ilieum resection 2007.


sr5599
Veteran Member


Date Joined Aug 2007
Total Posts : 1202
   Posted 4/7/2009 8:10 PM (GMT -7)   
I started vomiting after 3 weeks on Imuran. A few months my doc had me try 6-MP but I had the same results. Tolerated MTX fine though. Unfortunately it didn't help.
--40 year old female, dx as UC in '04 (1st symptoms in '03), switched to Crohn's in '05, 1 fistula, crohn's colitis, limited to large intestine  --rejected (reaction/didn't work): Asacol, AZA, 6-MP, MTX, Remicade, Humira, prednisone
--Prochymal in Phase III study (can't wait til it's approved!)
--started Tysabri 3/21/08 => STOPPED 10/3/08 - now 2 months into it & it was the right decision
--currently taking budesonide suppositories, 3mg at night.  SLIPPING big time.  Started Cimzia first dose 2/10/09.  cipro/flagyl cocktail 3/25/09  Dx Osteoporosis 10/08 started Forteo 1/27/09
--single mom to 11-yr-old girl

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