I don't have experience with Humira (considering starting soon), but why take it if it makes you feel worse? I had an allergic reaction to another med. After the first month, I told my doc that I didn't feel quite right since I started taking it (had a headache everyday and just felt generally off)...the doc thought it was just my body adjusting, so I brushed it off and waited for my body to acclimate. about 2 months after I started, the reaction came to a head and I ended up in the hospital for a week and a half. Normally, I'm good about taking my meds - during the time I was on this particular med I remember putting off my morning meds as long as possible. It was as if my body/subconscious knew something was wrong long before my conscious mind or my docs. I've since learned to listen for these clues. I'm not a doc and can't say whether you're having a reaction to Humira, just thought i'd share my expereince with you for what it's worth.