I had chest tightness when I was on Entocort. The GI (who is no longer my GI) told me there was no way the entocort caused it. But everytime I would take all 3 pills at the same time, I would have the same reaction. So then I took it upon myself and separated them, taking one in the morning, one at lunch and one at night. And the discomfort stopped. I told him what I did, and he said that if it worked that was fine. (now this is coming from a Dr. that treats his pts like monkeys and has no people skills) lol, sad, but very true!! But its good that you are going to get checked out, b/c you just never know!! good luck!