I have used pig whipworm eggs, TSO, with considerable success to dampen my UC (concurrently knocking out my seasonal hay fever completely), but I was unable to stay off of prednisone to avoid flaring and was eventually forced to resort to biologics, which so far have also failed to get me off pred. However, at least the biologics are "free" (paid for by healthy people's steep insurance premiums, to be exact) even though the actual cost of biologics, running into many tens of thousands a year, is much greater than the still steep cost of TSO. Unfortunately my GI won't let me combine the two therapies- that is the only reason I stopped TSO. I did try hookworm as well for my UC but it had no effect after 5 months so I killed them off. HW seems to be more effective for Crohn's, however, than for UC.
I am extremely interested in trying human whipworm for UC, which should be available shortly along with hookworm, and I would expect will be even more effective than TSO, since TSO is a pig whipworm. Bear in mind that the side effects of small, low dose worm infections on humans are minor (billions - yes you read that right, billions- of people have asymptomatic light infections) and reversible and that humans and these parasites have co-evolved for millions of years, whereas the side effects of biologics- which can include death- have been studied only for 10 years or so. The hygiene hypothesis is backed by science solid as a rock and the number of pubmed citations in this area keeps growing exponentially.
Pancolitis >20 years, allergic to all 5ASAs