My GI wants to put me on Remicade. He told me that if it works, you're usually on it at least 5 years, at which point he says it typically has a washout on effectiveness. Apparently, you can't start and stop it and then start again bc you'll build antibodies to it, so he's instead suggested we go with Imuran. Apparently on Imuran I could start it and use it for a few months or a year or so and go off it a while to see how I'm doing and then go back on it. Not so with Remicade. Remicade is also extraordinarily expensive, somewhere b/w $5,000 and $6,000 per infusion. My out-of-pocket expense would be 20 percent or $1,000-$1,200 per infusion. As of now, I'm trying alternative treatments to try and avoid both drugs, the expense and side effects. Best of luck!