Colazal is metabolized in the colon to mesalamine. Mesalamine is the main ingredient in Asacol and Pentasa. We have had several members develop disabling joint pain while on mesalamine medications. I would not advocate stopping a medication without confering with your doctor so your best bet is to call him/her up, tell them about
the joint pain and that you suspect the colazal. Perhaps they will have you stop taking it for a few days and see if the joint pain subsides.
Moderator Crohn's Disease Forum
CD, Ankylosing Spondylitis, lupus, small fiber peripheral neuropathy, avascular necrosis, peripheral artery disease, degenerative disc disease, and a host of other medical problems.