Colon Cancer Risk

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EruditePaul
Regular Member


Date Joined Jan 2006
Total Posts : 266
   Posted 6/15/2009 9:55 AM (GMT -7)   

One important colorectal cancer (CRC) risk factor is more than one-third of the colon involved with the disease as determined endoscopically.  Does this (more than 1/3 colon involvement) mean at the initial diagnosis or subsequent examination? 

 

My original 1994 original colonoscopy found mucosal changes from the sigmoid colon to the rectum and multiple aphthous ulcers in the cecum.  But since the treatment with the Chinese herbs, a 1998 colonoscopy and a 2003 colonoscopy came back negative without any microscopic inflammation detected in the entire colon.  I haven’t had a colonoscopy since 2003.   I still have stricture in my small bowel. 

 

Has anyone tried to use eClevelandClinic.org?  I costs something like $500 to get a second opinion from the Web. 


Diagnosed with CD in 1994;

In 1994 I was treated with Pentasa of no avail.  Have being treated with Chinese herbal medicines for over 10 years.


MikeB
Veteran Member


Date Joined Mar 2006
Total Posts : 1169
   Posted 6/15/2009 10:49 AM (GMT -7)   
Just a guess, but it seems reasonable -- the colon cancer risk from CD or UC seems to be largely determined by location of long term inflammatory processes that cause/trigger cellular dysplasia. So I would think the biggest factor is length of time for that inflammation, which makes sense, since they recommend colon cancer screening after longstanding disease. I would think that if you have experienced long term remission with no visual inflammation or ulceration on repeat scopes that your risk factor would be lower than someone with continuous active disease.

EruditePaul
Regular Member


Date Joined Jan 2006
Total Posts : 266
   Posted 6/15/2009 11:16 AM (GMT -7)   
Hi, Mike:  during my lunch walk, I was thinking maybe MikeB will be able to answer my question, because I remember you answered a different but somewhat related question quite a while ago.  Thank you!
 
Yes, I do have long term remission (13 years) and last 2 colonoscopy came back negative.  Unfortunately they did not do a biopsy during the last 2 scopes, because the GI doctors did not see anything there in the colon. 
 
The following is an excerpt from a CCFA publication on Page 317:  Inclusion in a screening and surveillance program is recommended for Crohn’s colitis patients who have major involvement of the colon. This has been defined somewhat arbitrarily as more than one-third of the colon involved with disease as determined endoscopically (not on biopsymaterial).32 
 

Diagnosed with CD in 1994;

In 1994 I was treated with Pentasa of no avail.  Have being treated with Chinese herbal medicines for over 10 years.

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