I've been on prednisone since last May, but am finally weaning off now that things are starting to genuinely improve. You may only have to be on it for a short time, but it depends on the person and symptoms.
They never seemed to make me any more vulnerable to sickness honestly. Neither has humira yet, and I have been on that since last September (started working wonders after 4-6 months).
Honestly, I know some people hate prednisone with a passion, but it has really helped me live a normal life and get rid of D. I couldn't walk or really function at all for several months then started taking 40 mg after diagnosis and was able to go out and eat that very day.
I know I say it a lot everywhere else, but you're not going to know until you try it. If you don't like what it is doing to it then you can always work it out with your doctor to quit. I highly recommend trying it though.
20 years old, Diagnosed with moderate to severe Crohn's and Colitis in May of 2008.
Currently taking: Prednisone 10 mg, pentasa 2 pills 4x a day, bentyl as needed, omeprazole in the morning, prenatal multivitamin, humira every other week, and Align probiotics prescribed by my GI.
Diet almost completely without refined sugars, wheat, flour, gluten, high lactose dairy, and/or junk food in general. bonniegriffith.blogspot.com/
Learning how to live again.
"He who has a why to live for can bear with almost any how."