Does any anybody know the current status of "Prochymal" Stem Cell research

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

Iram
Regular Member


Date Joined Jul 2003
Total Posts : 145
   Posted 6/17/2009 10:58 AM (GMT -6)   
There was thread here that suggested that the study failed. Any updates?

jmiller056
Regular Member


Date Joined Feb 2009
Total Posts : 57
   Posted 6/17/2009 1:07 PM (GMT -6)   
I haven't heard anything since Osiris announced that there may have been a design flaw in Phase 3. That was back on March 27. You can read about it on Osiris' site at: http://investor.osiris.com/releasedetail.cfm?Releaseid=373471 Hopefully the was the cells do work, and a Phase 4 gets going quickly!
23 y/o Male; Dx Crohn's Disease in 2001 at age 14.
Lost 3 inches of colon and 7 inches of ileum in 2004 bowel resection.
CD returns in October 2008, Starting the Maker's Diet June 17, 2009
Current meds: Pentasa: 3000 mg; Fibercon: 2 pills 3x; Imodium: 2 pills 3x
Been on: Prednisone, Flagyl, Cipro, Imuran, Entocort, Remicade
Kyrie eleison!


Reef08
Regular Member


Date Joined Dec 2005
Total Posts : 267
   Posted 6/17/2009 1:17 PM (GMT -6)   
There's nothing going on right now. No word on when the new Phase 3 trial will start. So much for it being fast-tracked by the FDA.

This drug looked like it was going to be the next big breakthrough in treatment and as our luck would have it, it gets delayed by a couple of years. It'll be a couple of years before the next group of drugs are approved.

vls
Regular Member


Date Joined May 2005
Total Posts : 166
   Posted 6/17/2009 2:42 PM (GMT -6)   

I'm currently in the study and it is officially over, according to the drs and nurses overseeing me in the study.  They have moved on to other trials (interleukin 18)  Osiris' stock plummeted, apparently after the news of the failed prochymal trial and future funding is questionable.  They continue to monitor those of us already in the trial for two years, why, I don't know, and neither do the drs.  They are done with it.  BTW, I'm waiting to find out if I developed Graft vs Host disease from the stem cell infusions.  I have to wait two weeks for the biopsies to come back because Osiris will not unblind the study to find out if I really did get the stem cells, but it sure is beginning to look that way.  Even if it would become available at some point, this therapy is not for me.

 


ivy6
Elite Member


Date Joined Sep 2005
Total Posts : 10404
   Posted 6/17/2009 4:08 PM (GMT -6)   
(((v.scho))) I'm so sorry.

:-(
Co-Moderator Crohn's Forum.

New meds thread


Reef08
Regular Member


Date Joined Dec 2005
Total Posts : 267
   Posted 6/17/2009 4:38 PM (GMT -6)   
v.scho said...
I'm currently in the study and it is officially over, according to the drs and nurses overseeing me in the study. They have moved on to other trials (interleukin 18) Osiris' stock plummeted, apparently after the news of the failed prochymal trial and future funding is questionable. They continue to monitor those of us already in the trial for two years, why, I don't know, and neither do the drs. They are done with it. BTW, I'm waiting to find out if I developed Graft vs Host disease from the stem cell infusions. I have to wait two weeks for the biopsies to come back because Osiris will not unblind the study to find out if I really did get the stem cells, but it sure is beginning to look that way. Even if it would become available at some point, this therapy is not for me.


That's really strange about the GVHD. As far as I know, GVHD only occurs during stem cell transplants when the immune system is knocked out by chemo, not from adult stem cell infusions. This is the first I've heard about it. Why would the doctors think you have it?

vls
Regular Member


Date Joined May 2005
Total Posts : 166
   Posted 6/17/2009 5:00 PM (GMT -6)   
GVHD was mentioned repeatedly in the consent forms I had to sign. I have a "dis-coloration" on my abdomen that is pretty horrific looking. It was preceded by itching and then a rash that began during the infusions. I can't count how many drs have looked at this and had no idea what it could be until finally one dermatologist suspected GVHD. I'll know in a couple of weeks.
New Topic Post Reply Printable Version
Forum Information
Currently it is Thursday, July 27, 2017 4:52 PM (GMT -6)
There are a total of 2,846,792 posts in 312,375 threads.
View Active Threads


Who's Online
This forum has 154193 registered members. Please welcome our newest member, jaywalker.
469 Guest(s), 15 Registered Member(s) are currently online.  Details
Alcie, PhotoGirl, 81GyGuy, island time, newuser22, Kellyrose1897, Scaredy Cat, Firoz rajohn, Dr WHO, judyjo2011, Octobrsky13, raspberryswirlgirl, jaywalker, ljimd, iPoop


Follow HealingWell.com on Facebook  Follow HealingWell.com on Twitter  Follow HealingWell.com on Pinterest
Advertisement
Advertisement

©1996-2017 HealingWell.com LLC  All rights reserved.

Advertise | Privacy Policy & Disclaimer