methotrexate with liver biopsy vs Imuran

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hana24
Regular Member


Date Joined Dec 2007
Total Posts : 354
   Posted 7/14/2009 6:13 PM (GMT -7)   
I was wondering if I could have some of youralls insight. I not not process Imuran very well and I am only on 25 mg and have low white blood count. I am have side effects of nausea and dizziness. My doctor says we could try methotrexate but I am scared of the liver biopsies. A lady in the remicade room said they will not put her out for the biopsies anymore and they are the most painful thing she has ever had done. I do not handle pain well. Does anyone have any experiences with this?
Jessica 27/F
Remicade, Entocort 3/day, Rowasa ,
Apriso/4 pills
Citalopram 20 MG
Align


Nanners
Elite Member


Date Joined Apr 2005
Total Posts : 14995
   Posted 7/15/2009 5:59 AM (GMT -7)   
I do not believe the would do a liver biopsy in order for you to take Methotrexate. You would only do that test if you were having liver problems. Maybe you should try switching to 6mp. It is similar to Imuran but breaks down differently. I found much less side effects on 6mp than I did with Imuran. Good luck!
Gail*Nanners* Co-Moderator for Crohns Disease and Anxiety/Panic Forum
Been living with Crohn's Disease for 33 years. Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, Calcium  w/Vit D, and Xanax as needed for my anxiety.  Resections in 2002 and 2005. Also diagnosed with Fibromyalgia, Osteoarthritis, and Anxiety. Currently my Crohns is in remission, but my joints are going crazy!
*Every tomorrow has two handles.  We can take hold of it by the handle of anxiety, or by the handle of faith"*

isergodur
Veteran Member


Date Joined Jan 2009
Total Posts : 831
   Posted 7/15/2009 7:09 AM (GMT -7)   
I just had my liver biopsy done three hours ago. It did not hurt that much, small pressure that's it. Good luck
24 year old female
Diagnosed with Crohn's disease in December 2008..
Medication - Asacol, Remicade, Cipralex and Cerazette.
My wonderful dogs :) ~ www.poodle.is ~


Bammer
Regular Member


Date Joined Mar 2008
Total Posts : 381
   Posted 7/15/2009 7:31 AM (GMT -7)   
I have been on methotrexate for ten months and have never had a liver biopsy. I do get bloodwork done monthly.

57 yr. old F dx. CD 07/07
Was on prednisone for three months but no medication for next 11 months.
Started weekly methotrexate injections 09/22/08.
Lap assisted sigmoidoscopy done May 11/2009


CrohnsPatient
Regular Member


Date Joined Feb 2008
Total Posts : 314
   Posted 7/15/2009 10:03 AM (GMT -7)   
Ive taken Methotrexate for many years and Ive never had to have one.

ZenaWP
Veteran Member


Date Joined Aug 2007
Total Posts : 884
   Posted 7/15/2009 10:27 AM (GMT -7)   
I had a liver biopsy while on 6mp because my liver enzymes were elevated and they had already tried a MCRP and ERCP.  The biopsy did not hurt at all and I was very surprised by how easy it was.  I was on methotrexate until last week and was just having monthly labs.  Enzymes are up again so they took me off of the mtx.  Doesn't make any sense to me to have biopsies while on mtx unless the bloodwork shows elevated enzymes and other tests (like MRCP and ERCP) are inconclusive.  My rheumy is making me stop the mtx until we can figure out if it's what elevated my enzymes this time. 
Crohn's Disease, Acid Reflux/Gastritis, Hashimoto's Thyroiditis, Endometriosis, Arthritis, Depression/Anxiety.  Too many meds to list them all.  =) 


hana24
Regular Member


Date Joined Dec 2007
Total Posts : 354
   Posted 7/16/2009 7:43 AM (GMT -7)   
Thanks for the info guys- the biopsy scares me more than anything
Jessica 27/F
Remicade, Entocort 3/day, Rowasa ,
Apriso/4 pills
Citalopram 20 MG
Align

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