Remicade and Imuran together?

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New Member

Date Joined Jul 2009
Total Posts : 1
   Posted 7/16/2009 11:04 PM (GMT -6)   
I have a 9 yer old daughter that after a year of Remicade treatments is not responding as well as when first administered.  Her GI is going to run lab work to see if she has built up antibodies to the Remicade.  But in the mean time he wants to put her back on Imuran along with the Remicade.  Everything I have read that is a big no, no because it increases risk factors for cancer.  Anyone taking both meds? 
Thank you.

Regular Member

Date Joined Feb 2009
Total Posts : 128
   Posted 7/17/2009 8:37 AM (GMT -6)   
I took both meds for a while and all my bloodwork came back fine. You just have to stay on top of it, your liver and your bloodwork will tell you if something is up. These two meds, basically a biologic and an immuno-modulator together are the best tandem going right now for treating crohns. That's what my gi just told me.

Terrible she's so young. I was showing symptoms when I was 13, and that was considered young then. Good luck.

I'm actually on 6-mp and Cimzia right now, which is just like what your doc is suggesting for your daughter, a TNF blocker and immuno-modulator.
I am a pre-30yr. old who has been diagnosed with Crohn's for 14 years.  Symptoms change from cramping and weight loss to severe anemia with fatigue and diarrhea. 
100mg mecaptopurine, 40mg Prednisone, Darvocet for dessert.  Starting Cimzia this week (fingers crossed).

Regular Member

Date Joined Sep 2006
Total Posts : 181
   Posted 7/17/2009 2:08 PM (GMT -6)   
I took both remicade and imuran, the GI just took me off Imuran after I asked if I really needed it. He indicated the that combo of remicade and imuran is most effective the first year of remicade.
33 year old Female
Diagnosed with CD 2006, had suffered long before 2006.
CD Meds: Remicade every 7 weeks & Imuran 50 mg,
Also have seasonal allergies, milk allergy, and asthma.

Elite Member

Date Joined Sep 2005
Total Posts : 10404
   Posted 7/17/2009 5:23 PM (GMT -6)   
Melnola, I don't think there's any harm in raising your concerns with your doctor. Your doctor should be aware of the cancer risk, and should be able to give you a better outline of his reasoning in recommending that your daughter take Imuran too.

All the best,

Co-Moderator Crohn's Forum.

Medications for Crohn's ~~ Diet and Nutritional Therapy for Crohn's

Regular Member

Date Joined Jun 2009
Total Posts : 354
   Posted 7/17/2009 9:36 PM (GMT -6)   
My doc took me off Imuran when I started remicade. But I have since built antibodies to the Remicade. She was willing to put me back on Imuran and take remicade. Like someone posted, keep her blood work up to date.Should be fine. Or do what my doc did. Took me off the remicade and has put me on Humira (just did my starter dosage today, 4 shots) I too lost the effectness of remicade. Most people who lose the effectness of remicade do switch to Humira and usualy in 3 months see a big difference.
Be careful of the anitbodies. I now suffer horrible arthritis type pain. It's crippling. I wouldn't want my worse enemy to have this pain let along a little 9 year old!
Good luck. Hope you sorted it out real soon. And she gets better.
24 year old woman. Crohn's all my life but diagnosed at age 18.Been on prednisone 8 times. which they will not give me anymore(doesn't work for me)I am on Prevacide for the ulcers I get in the stomach,pantesa. I've been on and off imuran,entocort,number of others I can think of. I have cronh's in the small bowel,colon,stomach. Since Nov 08 I've been suffering from RA which is just as bad as CD. haven't been able to work for the last 2 years. Awaiting to start Humira since being on Remicade for 1 year 4 months that no longer works.Hoping to get my life back with Humira.

New Member

Date Joined Jul 2009
Total Posts : 5
   Posted 7/17/2009 9:42 PM (GMT -6)   
i have been taking both meds now for 6 months ( 9 months for imuran) , no severe side effects have shown them selves as of yet
im on 100mg of imuran every night and about to start remicade every 8 weeks , though i have had it admistered 3 times already
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