LDN (MIxed results)

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Jin_Rou
Regular Member


Date Joined Aug 2009
Total Posts : 24
   Posted 8/28/2009 9:28 PM (GMT -7)   
After about 10 days on LDN, I have been getting mixed results. For the first time in a while I am having normal bowel movements instead of loose stools. However, stomach pain has not decreased. In fact, I am in more pain now than before.....A factor contributing to this however could be that I have resumed eating gluten before my biopsy next month, and the gluten could be aggravating my stomach and duodenum. LDN does not seem to be helping my stomach in the presence of gluten.

Its too early to tell what it is doing for my MS symptoms. It seems to be aggravating them, but then the symptoms go away again.

Keeper
Veteran Member


Date Joined Jun 2008
Total Posts : 1058
   Posted 8/29/2009 11:41 AM (GMT -7)   
If you are gluten intolerant, that involves an allergic response. That could possibly be more pronounced because of the LDN and its effect on the immune system. Just speculating - I don't know much about the action of LDN in detail.

Jin_Rou
Regular Member


Date Joined Aug 2009
Total Posts : 24
   Posted 8/29/2009 2:28 PM (GMT -7)   
Allergic is not really what is going on. Its more like an auto-immune intolerance, but its similar.

EMom
Veteran Member


Date Joined Aug 2007
Total Posts : 990
   Posted 8/29/2009 3:21 PM (GMT -7)   
Nick_Jinn, are you familiar with the yahoo groups dedicated to LDN? They might have some thoughts for you there. Also I have read that Dr. Bihari's protocol for effectiveness sometimes includes a diet to kill or at least reduce candida overgrowth. Just a thought...
Mom to 17 year old son diagnosed in June, 2007.
Omega 3s, digestive enzymes, probiotics, vit. C, calcium, vit. D3, a good multivitamin and SCD legal yogurt
Started The Maker's Diet in Sept. '07. Incorporate Specific Carbohydrate Diet (SCD) recipes, too. Med-free.
http://www.healingwell.com/community/default.aspx?f=17&m=984588
http://www.healingwell.com/community/default.aspx?f=17&m=1533705
http://www.healingwell.com/community/default.aspx?f=17&p=1&m=1262312


Keeper
Veteran Member


Date Joined Jun 2008
Total Posts : 1058
   Posted 8/30/2009 8:55 PM (GMT -7)   
Gluten intolerance would closely resemble the reaction to intestinal bacteria commonly blamed for Crohn's symptoms. It is caused by gluten protein being passed through the intestinal wall where the immune system becomes sensitized to it. Thereafter, any gluten reaching the immune cells will trigger inflammation. The initial sensitizing process requires both gut permeability and incomplete digestion of gluten to occur. Gluten is hard to digest, so that is a common occurrence and gut permeability is a frequent result of Crohn's. Once the immune system is primed for gluten, mast cells in the stomach lining would be triggered by gluten and the inflammation would propagate through the digestive tract since inflammation promotes gut permeability and gut permeability will trigger the immune system as the gluten passes through.
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