Breastfeeding and Pentasa

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New Member

Date Joined Feb 2006
Total Posts : 5
   Posted 9/22/2009 9:09 AM (GMT -6)   
I am currently almost 32 weeks pregnant and have been able to come off most of meds pre-pregnancy and am currently managing my Crohn's with Pentasa only.  Thankfully my Crohn's and my pregnancy have been getting along well so far!  My question is about Pentasa and breastfeeding.  I have read that it is ok to take during pregnancy as it is a category B, but that is may be contraindicated for breastfeeding.  Has anyone breastfed while taking Pentasa??  Thanks for your help!

Veteran Member

Date Joined Feb 2003
Total Posts : 1811
   Posted 9/22/2009 12:19 PM (GMT -6)   
Check out Dr. Hale's website on medications and mother's milk. Here is the link to the main site. You can search medicines from here:

Here is a link I could find on pentasa:

It looks like the risk is really going to be determined by the dose you are taking. Is it a high dose?
*activated your links*

Post Edited By Moderator (Nanners) : 9/22/2009 11:26:14 AM (GMT-6)

New Member

Date Joined Feb 2006
Total Posts : 5
   Posted 9/22/2009 12:53 PM (GMT -6)   
Thank you for the link! 
I am 'supposed' to take 4 pills 4 times a day, but I'd say the average is 2, maybe 3 times a day that I take it. 

Veteran Member

Date Joined Feb 2009
Total Posts : 7150
   Posted 9/22/2009 1:08 PM (GMT -6)   

(Visiting from the UC forum)

Here's a link to a great article on pregnancy and IBD.  You have to copy and paste it into your browser as clicking on it doesn't work for some odd reason.

It covers a lot of things, including breastfeeding and it's potential effect on flaring, as well as medications and breasfeeding. 

Mods, this article is in the UC resources thread on "our" page...maybe you'd like to add it to the Crohn's one as well? :)

Status: Remission since May 2009!
Symptoms began in November 2008, ~4 weeks after giving birth to my son.
Diagnosed with pancolitis on 1/30/09
Current meds: Apriso (4 0.375g pills ONCE!! daily), mesalamine enema twice weekly, Natural Factors Ultimate probiotic 12/12 Formula, OrthoNovum, multivitamin.

Regular Member

Date Joined Jul 2009
Total Posts : 342
   Posted 9/22/2009 6:38 PM (GMT -6)   
Hi..i take 12 pills a day..i was told..that they couldn't guarantee that it was safe..because not enough studys have been show whether or is both pregnancys..i did not breastfeed

 Crohn's anal fistula Lupus Hyperthyroid..Pentasa Remicade


Veteran Member

Date Joined Nov 2005
Total Posts : 1338
   Posted 9/23/2009 10:24 AM (GMT -6)   
I'm still breast feeding my 13-month old. I took Pentasa through pregnancy I just stopped taking it in July. I was on a smaller dose (5- 500mg caps/day as Rxed, but I tended to just take one dose usually 3 at night). I checked Dr. Hale and saw no concerns, my GI, Ped, Pharmacist and lactation consultant were all fine with it. My daughter is perfect and healthy. She's right on with all of her growth and development and absolutely perfect. I did stop taking it right after she was born, then had a few symptoms, so I started right back up and have been fine since.

Congrats on your new little one and good luck with a safe and easy delivery. Breast feeding is such a wonderful thing, I hope you can find a balance that works for you. I'm getting sad at the prospect of weaning my "baby" at the moment.

A couple things that might help:
- some meds are not okay at first b/c the babe nurses so much, but are ok taken later while breastfeeding or taken before bed once the baby lets you have a stretch of sleep. One trick I used with my hubby was to have him give one bottle of pumped milk in the night (if you can stand pumping or don't mind doing formula). I got a stretch of sleep and would take my Pentasa or whatever med I was taking immediately after I fed her, so I had the longest time between the med and the next nursing session.
- question any doc who quotes the pregnancy category to you when you are asking about a med and breast feeding. I had this happen with my PCP. They are two TOTALLY different standards. Some drugs may not cross the placenta, but will cross into breast milk and vice versa. You want to know the LI, LII, LIII ... info. Dr. Hale's site and book are the best.

Anyway, I'm very excited for you. Totally miss being pregnant (obviously). Take time to relax and enjoy the feeling of carrying the little one with you and to pamper yourself.

New Member

Date Joined Feb 2006
Total Posts : 5
   Posted 9/23/2009 1:32 PM (GMT -6)   
Thanks, Inflamed:) I appreciate hearing your story!! So we take about the same dose give or take a pill. I had originally wanted to come completely off Pentasa but that makes me nervous. My GI is surprised such a low dose is working ok so far and I don't want to risk a flare. I will definitely try the timing of doses with the timing of feeding. My regular OB and the specialists I see (not related to Crohn's, but other complications) said to watch for changes in stool consistency/frequency and that we would be able to tell if the meds are affecting the baby that way. Thanks again for the input, I really do appreciate it, and best of luck with you and your little one:)
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