New diet (restricting methianone) being researched for Crohn's

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PV
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Date Joined May 2006
Total Posts : 1177
   Posted 10/5/2009 8:15 PM (GMT -7)   
www.pr.com/press-release/147975

Never heard of methianone before. What do you folks think?

PV
Husband with Crohn's
Diagnosed March 2003 Ulcerative Proctitis
Diagnosed March 2008 Crohn's & C-diff, hospitalized 45 days
Canasa, Lialda, Remicade, VSL#3, Florastor
In Remission since June 2008
Stopped vancomycin for c-diff Jan 1 2009
C-diff free, until Sep 2, 2009
Fighting c-diff, I guess for life


medchrt1
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Date Joined Sep 2005
Total Posts : 517
   Posted 10/5/2009 8:40 PM (GMT -7)   
protein from food consists of amino acids... digestion makes the food protein into amino acids, the body then via polymerization of amino acids creates protein which is what makes skin, hair etc. after all ..the body continues this cycle and body parts such as bowel are continually being rebuilt. Then why this particular amino acid? we discussed alot about histidine (amino acid) as being a particular amino acid in certain types of milk,,,but the protein chains are so long that, isolation or restriction, of 1 particular amino acid of a protein chain, within the body is difficult. If the overall processing of the amino acids is flawed somewhere (as, in theory, being the genetic flaw associated with Crohns) elimination of a single amino acid while it has particular logic, the logic needs to be transparent. After all, by eliminating the building blocks of protein I really dont see where the junctions are now improved. But I am suspect that a amino acid might be a player/contributor to the problem at this point. When polymerizing, like when we make skin or nails is dependent on the ingredients (what the monomers are, in this case what amino acids are in the chain), as well as other factors which result in the properties of the final polymer that is built.

PV
Veteran Member


Date Joined May 2006
Total Posts : 1177
   Posted 10/5/2009 9:01 PM (GMT -7)   
:-D Ok, that was way way way over my head! Wow!

I think I may need to go to the wizard for a new brain to wrap my head around that one.

PV
Husband with Crohn's
Diagnosed March 2003 Ulcerative Proctitis
Diagnosed March 2008 Crohn's & C-diff, hospitalized 45 days
Canasa, Lialda, Remicade, VSL#3, Florastor
In Remission since June 2008
Stopped vancomycin for c-diff Jan 1 2009
C-diff free, until Sep 2, 2009
Fighting c-diff, I guess for life


Rider Fan
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Date Joined May 2008
Total Posts : 1445
   Posted 10/5/2009 9:05 PM (GMT -7)   
I think he's saying he's skeptical.
33 y/o male. Dx'ed in 1999. No surgeries.

Current meds: Humira 2/27/09. Proferrin iron pills.

Tried SCD, didn't work, now avoiding gluten and dairy.


Go Saskatchewan Roughriders!


medchrt1
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Date Joined Sep 2005
Total Posts : 517
   Posted 10/5/2009 9:16 PM (GMT -7)   
Taking an the analogy of the building block, glucose (sugar) is the molecule in a long chain carbohydrate. Similarly, for proteins, the small molecules are amino acids. There is only 1 product that I know which has refined protein and that is the Ensure drink. It has the individual amino acid already "refined". You can look at the ingredients. The study is attempting to restrict the one amino acid , methianone. This is an interesting idea. But to make such a food/drink is difficult. What exactly are these people going to eat? And I was questioning why this particular amino acid, which is essential to building protein. When the body sees it... is there something wrong? So someone hasnt just picked this amino acid out of a hat. It has sulfur, perhaps that is the problem area I dont know. sulfur is generally known to help with increasing the strength of polymers so elimination of it,,I wanted to understand why. Someone knows something more perhaps. Perhaps they do.

medchrt1
Veteran Member


Date Joined Sep 2005
Total Posts : 517
   Posted 10/6/2009 12:30 AM (GMT -7)   
i did find a company which has this a defined amino acid diet for research purposes:

http://www.harlan.com/research_models_and_services/laboratory_animal_diets/teklad_custom_research_diets/amino_acid_defined.hl

it is TD.90262 from harlan labs

heck why not provide this test across the board for each amino acid ,,then we can see how each effect us, not just restricting just this one amino acid, but its a start.
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