Uping Medication

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New Member

Date Joined Nov 2008
Total Posts : 17
   Posted 10/11/2009 12:49 PM (GMT -6)   
Hi everyone,

Happy thanksgiving to all in Canada.

On October 6, 2009 I had my colonoscopy. After my colonoscopy my GI indicated that he removed one small polyp and that there is very little activity in my colon. GI also indicated that he wanted to increase my medication from 800mg to 1600mg daily (asacol).

What I don't understand if the following;

1: five years ago my GI indicated that the activity in my colon was mild.
2: 1 1/2 ago there was a lot of activity. Which six months later I went into remission
3: Now he indicates very mild.

Why increase my medication when 5 years ago it was mild and now very mild?

Can Asacol acutally (maybe) put you in remission?
Have Crohn's for 5 years,
Meds: Asacol 800mg daily
Two Polps removed (non-cancer)

Veteran Member

Date Joined Feb 2003
Total Posts : 1811
   Posted 10/11/2009 2:16 PM (GMT -6)   
I don't know if Asacol can put you into remission or not, but it is specifically designed to break down in the large intestine/colon so it can work locally. 1600mg a day is only 4 pills, so that doesn't sound like a very big dose. I take 8 pills of asacol daily, sometimes 12. Have you asked your GI what his intention is? I would ask him his reasoning so you feel better about his decision OR so you can respectfully disagree. :) Good luck!

New Member

Date Joined Nov 2008
Total Posts : 17
   Posted 10/11/2009 3:20 PM (GMT -6)   
My GI did not provide his reason behind the increase. During that time I was still under and only left with a note from the GI.

However, I do see him in Dec

Thank you for your response
Have Crohn's for 5 years,
Meds: Asacol 800mg daily
Two Polps removed (non-cancer) one was carcinoid

Regular Member

Date Joined Apr 2009
Total Posts : 166
   Posted 10/12/2009 10:00 AM (GMT -6)   
I recently saw a new GI for a 2nd opinion. He was of the opinion that more is better, since there seems to be no harm in bigger doses. There seems to be a general view of younger doctors and those keeping up to date with research that this is true. When I was hospitalized in April the young GI on duty gave me huge doses of everything and when I came out my own GI reduced everything!!

My GI is an older man and does not follow the more is better theory. He is of the opinion that you should keep the medication to a minimum so that you do not have to keep upping the anti whenever you have a new flare. It sounds like your GI is reading the new research and is going with the new dosing recommendations.
44 years old. Diagnosed with moderate to severe Crohn's in April 2005. Hiatus hernia diagnosed in 2008. Had Crohn's under control until March this year when I had a major flare up and ended up in hospital. Diagnosis is now CD and IBS. Getting it under control again.
Currently taking: Prednisone 0 mg (as of this week!!), Salofalk 2000 mg, Nexium 40 mg, Calcium and Vitamin D, Matamucil, Yogurt for probiotics, Salofalk suppositories as needed.

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