New Anti_MAP Antibiotic in Development

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Regular Member

Date Joined Jan 2009
Total Posts : 45
   Posted 10/12/2009 1:04 PM (GMT -6)   
Here's an article about a new class of antibiotics in development that is specifically targeting mycobacteria.
This is encouraging news for Crohn's sufferer's given the theory that the disease is caused by . avium subspecies paratuberculosis (MAP).

"L-1 is a unique antibacterial target... SQ641 possesses exceptional activityagainst all members of the Mycobacteria family of bacteria, including... M. avium subspecies paratuberculosis, the potential etiological agent of Crohn's disease."

Veteran Member

Date Joined May 2006
Total Posts : 1177
   Posted 10/12/2009 1:52 PM (GMT -6)   
Any research that can help crohn's sufferers is good news! Thanks for posting this article. This is the first I've heard of this antibiotic research. I know there's another one being developed by Giaconda called myaconda. So, this is good news.

Husband with Crohn's
Diagnosed March 2003 Ulcerative Proctitis
Diagnosed March 2008 Crohn's & C-diff, hospitalized 45 days
Canasa, Lialda, Remicade, VSL#3, Florastor
In Remission since June 2008
Stopped vancomycin for c-diff Jan 1 2009
C-diff free, until Sep 2, 2009
Fighting c-diff, I guess for life

Veteran Member

Date Joined Apr 2006
Total Posts : 1885
   Posted 10/12/2009 8:46 PM (GMT -6)   

Daughter (22) Dx'd Crohn's 3/06. Misdiagnosed for two years, including by top pediatric Crohn's specialist as stress. No symptoms for the past two years. Recent colonoscopy shows stricture gone but still two spots of inflammation in TI. On Entocort since April 06. Never had D. Now using LDN to taper off Entocort. SCD multivitamin, homemade yogurt, 2000IU vitamin D3, 900+ mg calcium, 25 mg iron, monthly B12 shots, Krill capsules, occasional zinc. SCD diet modified to include potatoes and rice. 

Regular Member

Date Joined Sep 2009
Total Posts : 212
   Posted 10/12/2009 9:24 PM (GMT -6)   
Fanastic news! Thanks for sharing it!
Posts refer to my 9 year old girl
  • Started with 30 mg Prednisone, tapered off over 3 months.  Currently taking:
  • Pentasa, 3 blue horse-sized capsules, 2 x daily
  • Forvia multivitamin/mineral for Crohnies
  • Coromega and Omega capsule; Calcium
  • VSL#3;  Custom Probiotics; Culturelle; Align
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