flare and antibiotics

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Regular Member

Date Joined Oct 2008
Total Posts : 78
   Posted Today 8:54 AM (GMT -6)   
I've been enjoying a few months of symptom-free living, but now my symptoms are starting up again. I'm 100% sure this is due to antibiotics. Even my meds, which put me into remission about 10 months ago, don't seem to be helping this flare. I'm going to start watching my diet again, and look into probiotics. I've been eating lots of plain yogurt in hope of getting my gut stabilized, but this hasn't helped yet.
Has anyone had any experience with an antibiotic induced flare-up? Are there any special steps I can take to get back to remission? Ugh, what is so frustrating is the antibiotics, which were prescribed for a cough, didn't even help :(


Veteran Member

Date Joined Nov 2007
Total Posts : 4055
   Posted Today 9:46 AM (GMT -6)   
There are definitely some antibiotics that are worse then others. Are you still on them? I have found that I cannot take Augmentin. If you are off the antibiotics, then take some probiotics. You may have to experiment with what brand works best for you. I actually take Cipro (antibiotic) when my D gets bad and it helps me. Talk to your doctor if you are not getting better. Staying with a very mild diet, maybe even the BRAT (banannas, rice, applesauce and toast) may also help for a few days. Good luck
50 yr. old female, diagnosed with Crohn's in small intestine and terminal ileum Sept-Oct. 2007. Also have IBS, and had Salmonella Dec. '07
currently taking Pentasa- 4 500mg pills per day, Metamucil and colace for constipation, probiotics

Regular Member

Date Joined Nov 2008
Total Posts : 351
   Posted Today 10:39 AM (GMT -6)   
Cipro and Keflex get me.
27m - Dx January 2005: UC/Crohn's
Entocort 9 mg, Asacol 4 x 3, Flagyl 500mg x 3

Regular Member

Date Joined Mar 2009
Total Posts : 452
   Posted Today 10:58 AM (GMT -6)   
I recently tried Flagyl for 3 weeks.  I got about 2 weeks into it and I couldn't take anymore.  My CD got so bad that  I was living in the bathroom. 
Crohn's Disease since '88

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted Today 1:25 PM (GMT -6)   
I am like Gumby I cannot take Augmentin either it gives me horrible D. But the Cipro I recently took for my small bowel bacterial overgrowth worked really well for me. Definetly add some good probiotics. I use Primadolphilus Reuteri and have had great luck with it. Good luck!
Gail*Nanners* Co-Moderator for Crohns Disease and Anxiety/Panic Forum
Crohn's Disease for over 33 years. Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, Calcium  w/Vit D, and Xanax as needed. Resections in 2002 and 2005. Also diagnosed with Fibromyalgia, Osteoarthritis, and Anxiety. Currently my Crohns is in remission, but my joints are going crazy!
It's scary when you start making the same noises As your coffee maker.
*Every tomorrow has two handles.  We can take hold of it by the handle of anxiety, or by the handle of faith"*

Veteran Member

Date Joined Apr 2005
Total Posts : 3763
   Posted Today 2:15 PM (GMT -6)   
Some antibiotics are used specifically to treat CD. Others, used to treat other infections, can have a detrimental effect, or no effect at all. It seems to be hit or miss. I try to keep track of the antibiotics that have a harmful effect on my CD and try to avoid those, but sometimes those are the ones that will kill the infection and are a necessary evil.

Taking a good probiotic (at least two hours after any antibiotic) is always a good idea. You may have to try a few different brands to find one that works well for you. In this case it is true that you get what you pay for, so don't go super cheap. You don't have to go for the most expensive either, at least not at first. And don't buy a huge bottle until you know if it works for you.

CD 20 years officially, 30 unofficially. 3 resections '93, '95 '97
Managing with strict low residue diet, keeping symptoms to a minimum. All test show small amount of ulceration, still have occasional blockages. But still have a great time with my 2 daughters and husband!

Prednisone, 6MP,Prevacid, B12 shots, Bentyl, Xifaxan.....

Veteran Member

Date Joined Jun 2008
Total Posts : 1058
   Posted Today 3:44 PM (GMT -6)   
It is possible that the antibiotics have induced C difficile. It is very antibiotic resistant and it causes symptoms similar to CD. It is very hard to eliminate by normal means and you may need another course of different antibiotics to control it. Taking Florastor (S boulardi) can help control C diff so you could try that first. Unfortunately, C diff usually needs antibiotics to control it. If so, take Florastor along with the antibiotics. You might also try adding Culturelle as well since it is reported to help controlling antibiotic-related diarrhea.

Regular Member

Date Joined Apr 2009
Total Posts : 166
   Posted Today 3:48 PM (GMT -6)   
I took four rounds of antibiotics starting last December, and the doctor told me to expect a flare up. He was right, and it was a doozy. The trouble is, like Zanne says, sometimes you have to take them. I recently took Cipro for an infection, and it was OK, but as others have said, it depends on you and even on how your body is doing at that moment. I was tapering off Prednisone when I took the Cipro and it was fine. The probiotics are good to take while on the antibiotics, but take them a couple of hours apart otherwise the antibiotics counteract the probiotics.

I was told by my GI that the BART diet isn't worth much. Applesauce can actually be a problem when you are in a flare. I don't do well with it. I found in my last flare that in terms of fruit and veg I could only really do green beans, cooked carrots, bananas and diced peaches. Maybe a low-residue diet would be good to calm things down and let your medications get working again. You should be careful that things don't get out of control. Have you talked to your doctor about increasing your meds or adding some new ones for a short time?

A good site for a low residue diet is http://www.mayoclinic.com/health/low-residue-diet/MY00745

I hope you feel better. Get lots of rest.
44 years old. Diagnosed with moderate to severe Crohn's in April 2005. Hiatus hernia diagnosed in 2008. Had Crohn's under control until March this year when I had a major flare up and ended up in hospital. Diagnosis is now CD and IBS. Getting it under control again.
Currently taking: Salofalk 2000 mg, Calcium and Vitamin D, Matamucil, Yogurt for probiotics, Salofalk suppositories as needed.

Regular Member

Date Joined Oct 2008
Total Posts : 78
   Posted 10/27/2009 8:45 AM (GMT -6)   
Thanks for all the recommendations for probiotics-- I'll definitely look into that. I'm no longer on the antibiotics, I've been off them for about 3 weeks. I need to ask my pharmacy what they were so I can remember not to take that antibiotic again--I should have known better when the label itself said may cause diarrhea, but i had been feeling great and wrongly thought I could handle it.

Veteran Member

Date Joined Aug 2007
Total Posts : 1202
   Posted 10/27/2009 2:23 PM (GMT -6)   
I am still certain that the combo of Cipro and Flagyl, along with not being good about probiotics, landed me in the hospital for a week last April. I am very, very good about probiotics now whenever I take the antibiotics. I figure that, since my low-grade temps are back, I will be starting back on Cipro again sooner than later.

Good luck!
1 fistula, crohn's colitis, limited to large intestine
Compounded budesonide 3mg/daily, Started Cimzia first dose 2/10/09. Dx Osteoporosis 10/08 started Forteo 1/27/09

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