Both the sed rate and CRP have been lowered since the introduction of LDN. That, along with the leaky gut test, indicate an improved condition.
Of course, when she goes off the Entocort, we will keep checking labs to make sure the CRP and sed rate don't start going up.
We can't go by symptoms because she doesn't have any.
Btw, one 2001 article suggested zinc can play a role in helping a leaky gut. She did test deficient in zinc. However, when we try to supplement with zinc then her iron goes down. If we try to up the iron the zinc goes down. ANd this happens even if she takes iron and zinc hours apart. I've checked all the journals and we seem to be in the dark ages when it comes to knowing how and when to take supplements. It's all trial and error.