Celebrex/COX-2 inhibitors/joint pains

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

uklass
Regular Member


Date Joined May 2009
Total Posts : 65
   Posted 11/1/2009 8:04 AM (GMT -7)   
Hi folks
 
I've having problems with joint pains - CT scan showed sacroiliitis but I get really aching elbows and hands as well. I'm having an MRI scan in a couple of weeks time (not sure what this will look for) and hopefully might get a diagnosis as to what it might be ( I haven't been referred to a rheumatologist yet - gastro doc says its pretty much same treatment as Crohn's drugs-wise if arthritis). My gastro consultant has prescribed me Celebrex  - in the past I would have used Ibuprofen but since this is not allowed now he says COX-2 type next best thing. He wants me to consider Sulfazalazine but since my Crohn's (guts) is ok with mostly IBS symptoms (being managed by diet) I am reluctant to take anything else other than the Asacol I am now on as a maintenance med. The Celebrex eases some of the symptoms but not as well as Ibuprofen did and so I thought I'd sift through posts on this site to see what others have experienced- not many people appear to use Celebrex: is this because you are on stronger drugs for your Crohn's and/or arthritis, or is there something I should know about? I know some previous ones were taken off the market a few years ago but haven't seen any scary stuff about Celebrex.
 
Any views or advice welcome
 
Penny x
Diagnosed aged 31 in 1996 - emergency surgery (right hemicolectomy). Thought I'd only get 'it' once and have lived in relatively blissful ignorance, apart from a couple of hospital stays for obstructions (scar tissue), until March 09....major surgery, 2 resections, fistula and now only 195cm small bowel left. Not on any meds at present except B12 injections but know there will be some. Just getting used to my 'new' body and it's limitations........ July 09 hospital stay for obstruction & tests show disease back: now on Asacol and waiting to see which treatment I'm put on
 
Penny x


Nanners
Elite Member


Date Joined Apr 2005
Total Posts : 14995
   Posted 11/1/2009 8:16 AM (GMT -7)   
I am not sure we are supposed to use Celebrex as it is a sorta like an Ibrufen type med and could cause bleeding in us. If I were you I would try the Sulfazine. Its a med in the same family as the Asacol and have heard if you can use Sulfa type drugs this is helpful for the joint pain. I am allergic to sulfa so I can't use it. Good luck!
Gail*Nanners* Co-Moderator for Crohns Disease and Anxiety/Panic Forum
Crohn's Disease for over 33 years. Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, Calcium  w/Vit D, and Xanax as needed. Resections in 2002 and 2005. Also diagnosed with Fibromyalgia, Osteoarthritis, and Anxiety. Currently my Crohns is in remission, but my joints are going crazy!
It's scary when you start making the same noises As your coffee maker.
*Every tomorrow has two handles.  We can take hold of it by the handle of anxiety, or by the handle of faith"*

Julia Hill
Veteran Member


Date Joined Mar 2008
Total Posts : 543
   Posted 11/1/2009 9:50 AM (GMT -7)   
Hi,

I did read the side effects of Celebrex and bleeding in the intestine is one of them. I think I would talk this over with my GI as you really don't need issues like this down the road. This med was just prescribed for my husband so I have been checking it out as I know it was discontinued about 5 years back in Canada for the side effects.

Julia

contrymom
Regular Member


Date Joined Oct 2009
Total Posts : 39
   Posted 11/1/2009 10:26 AM (GMT -7)   
I used to take Celebrex and Mobic, for Joint pains etc. Switched to Mobic, about 10 years ago when things started coming out about side effects with Celebrex. Mobic worked wonderful.

But I just asked my Gastro Dr, about me taking either one again, and I just got the *LOOK* from him, as if to say, Um, do you want to make your Crohns worse????

When I had my 3rd treament of Remicade Sept 30th 2009, it basically attacked my joints and arthritis every where on my body, I couldn't even walk that night. So it was an amulance trip to the ER, My husband called the Er first and explained the side effects that I was having and that I had just gottne a treatment of Remicade that mornung. i've just been diagnosed with Crohns in the begining of Aug 09. so this is all new to me.

So now for pain that is every where still in my body, I take 1- 30mg tablet of Oxycodone every 4 hrs. I can only take them early in the am, and early afternoon, as they get me *wired* and if I take them to late I can't sleep.

So now late afternoon I take Vicodine 2-3 7.5 mg tablets then again at bed time. So this way my body is some what functionable.

The 3rd treatment of Remicade has really attacked my joints, nerves, muscles etc every where in my body with either pain or Tingly and numbness.

I'm just so afraid to try Celebrex or anything of the such, as I do not need anything ti further cause more problems with the Crohns.

Hugssssss and I hoep this helps.

Sa;;y

My husband is on both Celebrex and Flexeril. Celbrex is 2 100mg pills a day, and the Flexeril is 1 10mg tablet 3 times a day. He takes them for his neck and shoulder problems. If he doesn't take them as he is supposed to, he will get a massive head ache.
Sally from Milton NH.   
Prevcid  DR   (1)  30mg  tablet every morning 
Potassium CL ER  (1) 20mg in the morning 
Ascecol EC  (4) 40mg tablets 3 X a day 
Pomrthazine  (1) 12.5 mg  when needed for a quesy stomach which is basically 3 times a day. 
Dicyclomine (1) 20 mg tablet 3X a day 
Oxycodone  (1) 30mg tablet every 4-6 hours.  
Vicodone  APAP (2-3) 7.5-750 At  bed time  
Steroids do not work for my Crohns at all
 
 
 
 


medchrt1
Veteran Member


Date Joined Sep 2005
Total Posts : 517
   Posted 11/1/2009 4:31 PM (GMT -7)   
you can read wikipedia http://en.wikipedia.org/wiki/Cyclooxygenase for COX. but as far as which enzyme is associated with COX 1 and COX2 they are different....
Thus by inhibiting COX (what you are doing is interferring with a particular enzyme). By inhibiting this enzyme you lose the bowel barrier prostagladin production especially for COX1. while some say the COX2 category is lesser evil it is actually a different enzyme that you are interferring with, and the 'result' from selectivity gives different side effects. I think it would be a good question for the doctor and to receive a more informed response beyond the "look". After all, there is no lesser evil if you inhibit any enzyme from performing a task for the sake of pain relief.

DFBDAR
New Member


Date Joined Nov 2009
Total Posts : 3
   Posted 11/14/2009 12:58 AM (GMT -7)   
Iwas on celebrex for 6 years with no problems. Its was a miracle drug for me until it was taken off the market for a short while. It is easier on your stomach than ibuprophen.

Nanners
Elite Member


Date Joined Apr 2005
Total Posts : 14995
   Posted 11/14/2009 7:33 AM (GMT -7)   
DFBDAR do you have Crohns? The reason I ask is Ibruprofen like meds are not allowed for us Crohnies and they can cause bleeding. Ibruprofen triggered one of my worst flares.
Gail*Nanners* Co-Moderator for Crohns Disease and Anxiety/Panic Forum
Crohn's Disease for over 33 years. Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, Calcium  w/Vit D, and Xanax as needed. Resections in 2002 and 2005. Also diagnosed with Fibromyalgia, Osteoarthritis, and Anxiety. Currently my Crohns is in remission, but my joints are going crazy!
It's scary when you start making the same noises As your coffee maker.
*Every tomorrow has two handles.  We can take hold of it by the handle of anxiety, or by the handle of faith"*

AzJohnny
Regular Member


Date Joined Sep 2006
Total Posts : 171
   Posted 11/14/2009 2:59 PM (GMT -7)   
Hi Penny,

I was diagnosed with Crohn's in 2006. I had already had post surgical arthritis for some years and had been taking aspirin for it. After getting Crohn's I discovered for myself on the internet that aspirin and the other NSAIDs were a bad idea. My Primary Care Physician (PCP) put me on Celebrex with the knowledge of my GI and so far it has helped without causing any problems.

Keep in mind that we all react differently to meds so the same may not be true for you.

I only take it when I really need it now and it could start causing me problems at any time, so if you find something that helps your arthritis without hurting your guts, please let me know.

Gook luck.
AzJohnny
 
I feel a whole lot more the way I do now than I did a little while ago.

New Topic Post Reply Printable Version
Forum Information
Currently it is Saturday, December 03, 2016 4:50 PM (GMT -7)
There are a total of 2,732,280 posts in 301,006 threads.
View Active Threads


Who's Online
This forum has 151168 registered members. Please welcome our newest member, 14YearOldKid.
312 Guest(s), 6 Registered Member(s) are currently online.  Details
Chask, Girlie, pmm73, DennisinNY, Oranged, iPoop


Follow HealingWell.com on Facebook  Follow HealingWell.com on Twitter  Follow HealingWell.com on Pinterest
Advertisement
Advertisement

©1996-2016 HealingWell.com LLC  All rights reserved.

Advertise | Privacy Policy & Disclaimer