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New Member

Date Joined Jul 2009
Total Posts : 17
   Posted 11/14/2009 5:44 PM (GMT -6)   
Is anyone taking Apriso?  I found out about it today at a Crohn's symposium.  It's been out for 6 months and its an extended release version of it's taken once a day.   Thinking about switching my son to this instead of Pentasa.   Any feedback would be appreciated.   

Veteran Member

Date Joined Feb 2009
Total Posts : 7150
   Posted 11/14/2009 6:33 PM (GMT -6)   
(popping in from the UC forum)
I switched from Asacol to Apriso in July or so, and LOVE it so far. I was in remission when I switched, and was a bit apprehensive about switching (why rock the boat, you know?), but I was also having a LOT of trouble (even with an alarm on my cell phone) remembering my noon dose, and sometimes my evening dose of Asacol. I was also seeing capsules with medicine still in them in my stool, and since Apriso dissolves at a lower pH than Asacol, and UCers (not sure about CDers) are believed to have lower gut pH, I thought it was worth a shot. Since I switched, I feel that my remission is a bit more solid, but that could just be because I was further from the flare and things just got that much less inflammed.

I'm not familiar with Pentasa in terms of what part of the digestive tract it treats. I'm pretty sure Apriso starts dissolving in the terminal ileum, but I'm not sure. I'd ask your son's doctor to make sure Apriso will treat the same area that Pentasa does.
Status: Remission since May 2009!
Symptoms began in November 2008, ~4 weeks after giving birth to my son
Diagnosed with pancolitis on 1/30/09
Meds: Apriso (4 0.375g pills ONCE!! daily), mesalamine enema twice weekly, Natural Factors Ultimate probiotic 12/12 Formula, OrthoNovum, multivitamin.  Used prednisone (starting dose 40 mg) to get into remission.
Thread with links to UC resources and  information:

New Member

Date Joined Jul 2009
Total Posts : 17
   Posted 11/15/2009 8:12 AM (GMT -6)   
Thanks for the reply...that's promising. My son actually has CD in the terminal ileum and where he's a teenager, our doctor is only requiring him to take his Pentasa 2x a day, morning and night. I feel like this will provide more of a 24 hour protection, so I can see why you feel that your remission is more solid. By the way, at the CCFA symposium yesterday, they recommended Fish oil, probiotics (which you already take), curcumin and boswellia. I'm going to add curcumin to my son's regiment. I may add Boswellia as well....need to research a little more.
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