50-100 Different IBDs within next 5 years

New Topic Post Reply Printable Version
[ << Previous Thread | Next Thread >> ]

GDen
Veteran Member


Date Joined May 2009
Total Posts : 703
   Posted 11/26/2009 7:08 PM (GMT -7)   
I recently saw David T. Rubin (www.uchospitals.edu/physicians/david-rubin.html) speak and he said he expects there to be a major reclassification of IBD within the next five years into as many as 50 to 100 different types. I think I recall he said many will be defined by what specific parts of the intestines they occur in. Plus I imagine whether they're stricturing, fistulizing, or inflammatory will be considered, and whether they're extraintestinal as well. I was pretty amazed by his comment, particularly since having fairly recently learned there are three different types of CD. It was great hearing David speak and he really seems up-to-date on the latest in IBD.

pb4
Elite Member


Date Joined Feb 2004
Total Posts : 20576
   Posted 11/26/2009 8:34 PM (GMT -7)   
Intersting...there are 5 subtypes of CD to date;

Many docs already refer specfically to CD when it's "fistulizing CD" or "Stricturing CD" or "inflammatory CD", so none of that is new info.

:)


*******************
pb, as previously requested, please just provide a link instead of just copying and pasting onto the forum. Copying and pasting uses server space that - ultimately - Peter is going to have to pay for.

If you *must* copy, please provide a link and attribution as well. It's only polite to acknowledge the original author of the material.

Thanks. btw, I've been noticing your efforts to stay within the rules lately, and appreciate it. - Ivy.

pezdog
New Member


Date Joined Nov 2009
Total Posts : 16
   Posted 11/26/2009 11:00 PM (GMT -7)   
When are we going to hear about 50-100 cures for this awful crap???????
16 year old male. Symptoms since 12 years old and diagnosed with Crohns disease last year.
Imuran 100mg, Protonix 400mg, Prednisone 40 mg.
6000IU fish oil, 6-10,000 IU vitamin D, Acidophilus 1Billion count, multivitamin, 150 mg Iron (slo Fe)
 
Somebody help me!


GDen
Veteran Member


Date Joined May 2009
Total Posts : 703
   Posted 11/26/2009 11:01 PM (GMT -7)   
Great post pb4. I was vaguely aware of those types of CD. Any idea how many types of UC there are?

pb4
Elite Member


Date Joined Feb 2004
Total Posts : 20576
   Posted 11/26/2009 11:08 PM (GMT -7)   
This link is quite informative re; subtypes of UC...


Read article....

BeeSting
Regular Member


Date Joined Nov 2008
Total Posts : 392
   Posted 11/28/2009 4:59 AM (GMT -7)   
Mine is jejunoileitis,
 
It's my understanding that this is a very little group. I remember to have read that less than 5 - 6 % of all Crohns cases are having jejunoileitis. The symptoms are those you're mentioning, I have also blockages due to the inflammation, so prior to starting with LDN my days were exact like written about jejunoileitis,
my point to write about this now is: if LDN helps my type of Crohns, by reducing the inflammational activity and ridding all the symptoms, may be it could help more people? /Bee

CrohnieToo
Veteran Member


Date Joined May 2003
Total Posts : 9448
   Posted 11/28/2009 11:23 AM (GMT -7)   
Hmmmm. I guess I have Crohn's ILEITIS. My Crohn's first struck in the mid-ileum. Actually as near as I can determine from my old medical records, it seems to have struck at the proximal end of the 3 feet usually referred to as the terminal ileum. There was some slight malformation or narrowing of the near distal end of the terminal ileum - which hasn't changed in 31 years. The original site at the "mid-ileum" had to be resected in 1978 and has now narrowed to a high-grade partial obstruction that so far, thank God, is not causing any but minor problems/symptoms the last 10 years.

The reason I say I'm GUESSING mine is Crohn's ileitis is because ... knock, Knock, KNOCK ... I've not had any fistulizing or absesses. Gawd, I HOPE I didn't jinx myself by putting that into words and printing it!!!!!!!!!
Some people are like Slinkies... Not really good for anything, but they still bring a smile to your face when you push them down a flight of stairs.


CrohnieToo
Veteran Member


Date Joined May 2003
Total Posts : 9448
   Posted 11/28/2009 11:25 AM (GMT -7)   
I wonder how closely tied to the various genes they are finding are involved w/Crohn's disease the tentative classifications will be?
Some people are like Slinkies... Not really good for anything, but they still bring a smile to your face when you push them down a flight of stairs.


pb4
Elite Member


Date Joined Feb 2004
Total Posts : 20576
   Posted 11/28/2009 12:35 PM (GMT -7)   
Mine is crohn's colitis (although when I first became sick 18 yrs ago it was affecting my small bowels as well as my rectom and anus with the perianal crohn's skin tags) it has remained constant in my colon, on and off in my rectom and constant with the anal skin tags....BUT I've been very lucky that I have not had the common issues linked to crohn's colitis of fistulas, joint pains, abcesses...so not everything is written in stone, I'm just glad I'm not the classic case of crohn's colitis having the above common issues related to CD affecting the colon....mind you the perianal crohn's skin tag issues have/are been bad enough.

:)

pb4
Elite Member


Date Joined Feb 2004
Total Posts : 20576
   Posted 11/28/2009 12:36 PM (GMT -7)   
Very closely, infact the latests cluster of about 30 genes they have found is connected to the severity and behaviour of CD over time for each patient.

:)

CrohnieToo
Veteran Member


Date Joined May 2003
Total Posts : 9448
   Posted 11/28/2009 12:45 PM (GMT -7)   
I kind of guessed as much, pb4. I donated a blood sample to the genetic blood testing study for Crohn's. The research facility offered to pay for the blood draw but my local hospital lab did the draw at no charge because it was for research and sent the sample to the research facility, again at no charge.

It should be interesting eventually to see the results of these classifications they come up with.
Some people are like Slinkies... Not really good for anything, but they still bring a smile to your face when you push them down a flight of stairs.


BeeSting
Regular Member


Date Joined Nov 2008
Total Posts : 392
   Posted 11/28/2009 2:03 PM (GMT -7)   
Crohnie Too, don't print what you've written about the fistulas, and absolute don't hang the print up on the wall, the "wannabie-fistulas" may read it...;)!
 
Pb4, thank you for writing about the different types of Crohns. If the doctor is right that we'll know about 40 - 50 more types in the future, it could be easier to find suitable medicines.
 
Interesting that they've found SO many genes that may be trigged to create Crohns....But what triggers the Crohns? I think that the genes we're having makes us vulnerable in getting Crohns in the first place. But something may trigger the genes, imho I think that could be the food we eat. Not to claim that all of us eats what we call unhealthy food, because I think many of us have been eating quite healthy food our entire life. My mother has always been making all the food from fresh vegetables, meat and fish, and have never bought a canned whatever in her life. I continued to make food like her when I got my own household, baked my own bread and almost never use any canned stuff.
 
 
But I have to say that to a great degree suspect flour and sugar. I am not that suspicious to milk, but I try to avoid drinking too much of it. I make my own home made yogurt the SCD way and I avoid sugar/wheat. I feel much better by doing this, and I know a lot of Crohnies does. But then again, we're different and reacts to different food and may have different genes! I also guess that our immune defence may be triggered more and more when the inflammation is increasing, and the genes may play a role in telling the immune defence how to react. / Bee

Post Edited (BeeSting) : 11/28/2009 2:19:00 PM (GMT-7)


GDen
Veteran Member


Date Joined May 2009
Total Posts : 703
   Posted 11/28/2009 5:02 PM (GMT -7)   
David Rubin also said that 31 confirmed IBD genes had been discovered by 2008, and 50 by 2009. NOD2/CARD15 (I don't know what that means) was discovered in 2001. And he said the IL23 receptor gene protects against IBD.

Escalador
Regular Member


Date Joined Jul 2009
Total Posts : 103
   Posted 11/28/2009 5:21 PM (GMT -7)   
51? that just means its not gene related

GDen
Veteran Member


Date Joined May 2009
Total Posts : 703
   Posted 11/28/2009 5:25 PM (GMT -7)   
New Topic Post Reply Printable Version
Forum Information
Currently it is Monday, December 05, 2016 5:55 PM (GMT -7)
There are a total of 2,733,258 posts in 301,097 threads.
View Active Threads


Who's Online
This forum has 151238 registered members. Please welcome our newest member, ejc61.
334 Guest(s), 16 Registered Member(s) are currently online.  Details
martha, bluelyme, MustangSally52, Lymepilot, Artist Mark, Lilyblues22, NiceGuyEddie, Scaredy Cat, 142, jdm99, jabele, wearyRAsufferer, k07, Tall Allen, julymorning, Graytech


Follow HealingWell.com on Facebook  Follow HealingWell.com on Twitter  Follow HealingWell.com on Pinterest
Advertisement
Advertisement

©1996-2016 HealingWell.com LLC  All rights reserved.

Advertise | Privacy Policy & Disclaimer