Safer Steroids?

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Veteran Member

Date Joined May 2009
Total Posts : 703
   Posted 11/27/2009 7:54 PM (GMT -6)   
I recently heard that safer, more targetted steroids are being developed. Does anybody know their names and whether any are available yet?

Veteran Member

Date Joined May 2006
Total Posts : 1177
   Posted 11/27/2009 8:55 PM (GMT -6)   
One of course is entocort - this delivers mostly to the small intestine, and is very minimally systemically absorbed.

There is one in development called colal-pred. The last time I checked, this was is stage 3 testing. This one delivers prednisone to the colon, and like entocort is very minimally systemically absorbed.

I don't know of any others.

Husband with Crohn's
Diagnosed March 2003 Ulcerative Proctitis
Diagnosed March 2008 Crohn's & C-diff, hospitalized 45 days
Canasa, Lialda, Remicade, VSL#3, Florastor
In Remission since June 2008
Stopped vancomycin for c-diff Jan 1 2009
C-diff free, until Sep 2, 2009
Fighting c-diff, I guess for life

Regular Member

Date Joined Oct 2009
Total Posts : 253
   Posted 11/27/2009 9:08 PM (GMT -6)   
I was on entocort for awhile (about 5 months) and never had any negative side effects either than a bit of a swollen face... it was really good for me. I'm scared of the harsher ones :(
19 y/o female, diagnosed crohns december 2008
currently taking 500 mg pentasa 4x daily

Elite Member

Date Joined Apr 2005
Total Posts : 14995
   Posted 11/28/2009 11:18 AM (GMT -6)   
I remember when I came out of my 20 year remission I was shocked that the meds hadn't changed much at all. Now there is Entocort, 6mp/Imuran and all the biologics. I was treated for that first flare after remission with the same meds, Pred and Pentasa that I had used in 1980, later changed to Asacol. We really do need more research for our disease. JMHO
Gail*Nanners* Co-Moderator for Crohns Disease and Anxiety/Panic Forum
Crohn's Disease for over 33 years. Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, Calcium  w/Vit D, and Xanax as needed. Resections in 2002 and 2005. Also diagnosed with Fibromyalgia, Osteoarthritis, and Anxiety. Currently my Crohns is in remission, but my joints are going crazy!
It's scary when you start making the same noises As your coffee maker.
*Every tomorrow has two handles.  We can take hold of it by the handle of anxiety, or by the handle of faith"*
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