Long-Term Acetaminophen Use?

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GDen
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   Posted 11/29/2009 5:43 PM (GMT -7)   
Think there's any dangers of long-term acetaminophen use? I've take it almost every day, usually no more than 1/4 to 1/2 the recommended max dose. I've encountered several people that think there may be hazards, but I haven't found anything official saying so. I did find several statements from drug companies saying acetaminophen is quite safe, even long-term, when directions are followed. I get LFTs every 2-4 weeks, and they've all been fine.

73monte
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Date Joined Mar 2007
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   Posted 11/29/2009 7:04 PM (GMT -7)   
No expert here, but the one thing that I always hear the Nurses where I work talking aobut is how hard Tylenol is on the Liver. You may want to check the net on that for more info.
 
Tom. 
My daughter was diagnosed Feb. 19/07, (13 yrs. old at time of diagnosis), with Crohn's of the Terminal Illium. Has used Prednisone and Pentasa. Started Imuran (02/09), had an abdominal abscess (12/08). 2cm of Stricture.


MAG102886
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Date Joined Jul 2008
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   Posted 11/29/2009 7:08 PM (GMT -7)   
Tylenol is hard on the liver, I don't know what extent you have to be taking it to start hurting yourself though.
Dianogsed with Crohns: At 16 years old. 22 years old now.
Surgeries:2 Bowel Resections, Gallbladder Removed, 3 Abscess Cleanings
Current Meds: Cimzia, Methorexate, Vitamin B12 (injections), Nexium.
Next Surgery: Nov. 20th to Take Down Abdominal Fistula!!!
 

LMills
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Date Joined Apr 2008
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   Posted 11/29/2009 7:09 PM (GMT -7)   
Try looking over these:

http://headaches.about.com/od/medsarticlesandinfo/a/acet_kellie.htm

http://www.mnpoison.org/index.asp?pageid=260

http://www.cbsnews.com/video/watch/?id=1173509n

I'm sure that as long as you're responsible it's fine, but I would be careful if you're taking it everyday. Don't the instructions say not to take it beyond a certain point?? I know I've disregarded them in the case of cystex and immodium, but I got the okay from my doctor on the latter...
Diagnosed with Crohn's in May of 2008.
Currently taking: Prednisone, pentasa, omeprazole, and humira. Using probiotics and a multivitamin.
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Former58D
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Date Joined May 2009
Total Posts : 173
   Posted 11/29/2009 7:52 PM (GMT -7)   
I believe tylenol liver damage kills more people each year than any of the other drugs we Crohnies are accustomed to. Granted that is due to massive overdoses. Some medications, like vicodin, have a tylenol mix and people forget that and take too much. Just take care and watch your intake. If you can, get a quarterly or semiannual liver functions test.
"What can't be changed must be endured" - unknown

DX with distal Crohn's colitis Oct 2007, predominantly in rectum
Colozal (750mg): 3 pills 3xdaily
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Steakum824
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Date Joined May 2003
Total Posts : 40
   Posted 11/30/2009 5:30 AM (GMT -7)   
I've been taking Tylenol w/codeine for about 5 years. I am up to 8 pills a day, not just for pain but the codeine (which constipates "normal" people) actually makes me regular for a few days a week. They are only 300mg per pill, so I am at 2400 of acetaminophen per day, for at least 15 days of each month. I pound my system with it, then I run out and have to wait another week or two for the refill, so my liver does get a bit of a break, hopefully enough of one.

lilcrohnieUK
Regular Member


Date Joined Dec 2007
Total Posts : 414
   Posted 11/30/2009 6:07 AM (GMT -7)   
Whats the UK equivalent of Tylenol/acetaminophen? If there is one?!
 
Steakum I'm like you I take codeine for bowel control. Happened by complete accident soon after I was first diagnosed - didn't help with the pain but finally put an end to the diarrhea and accidents so the doctors started prescribing it to me for that purpose rather than pain! Best coincedence that ever happened to me! Only thing that sucks is it means I now have an insanely high tolerance to pain meds - not good if I flare!
 
 
 
 


Steakum824
Regular Member


Date Joined May 2003
Total Posts : 40
   Posted 11/30/2009 6:21 AM (GMT -7)   
Same here lilcrohnie....I recently had some Vicodin for a dental issue, and it calmed things but didn't really kill the pain. Also, when I have my yearly colonoscopy, my GI now has me knocked out with Propofol, because according to him the Versed and Demerol isn't enough to keep me out....I only have vague memories of moving around and talking while "under". I haven't been told so, but I attribute this to high tolerance brought on by Codiene use.   What can ya do.
 
*Sorry I have had to edit your post, medical mj is not allowed to be discussed on this forum*  Thanks for your understanding.  Rule #2.

Post Edited By Moderator (Nanners) : 11/30/2009 7:37:13 AM (GMT-7)


CrohnieToo
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Date Joined May 2003
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   Posted 11/30/2009 8:30 AM (GMT -7)   
I'm on Imuran so have a blood draw every 3 months that checks liver function.

I do usually take one Tylenol Rapid Relief (500 mg) at night at bedtime as it helps w/the minor aches and pains to get to sleep. I just don't sleep as well w/o it.

I have read that taking Tylenol w/food tends to reduce the risk to the liver. I'm guilty of not doing that as eating that close to bedtime isn't conducive to good sleep.
Some people are like Slinkies... Not really good for anything, but they still bring a smile to your face when you push them down a flight of stairs.


Nanners
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Date Joined Apr 2005
Total Posts : 14995
   Posted 11/30/2009 8:43 AM (GMT -7)   
I take Percoset for pain daily, although I only take 1/2 tab 3-4 times a day. It has tylenol in it. I really think you are okay as long as you don't go over the recommended daily dosage, and if I understand your post correctly you aren't even close to the daily dosage. Good luck!
Gail*Nanners* Co-Moderator for Crohns Disease and Anxiety/Panic Forum
Crohn's Disease for over 33 years. Currently on Asacol, Prilosec, Estrace, Prinivil, Diltiazem, Percoset prn for pain, Zofran, Phenergan, Probiotics, Calcium  w/Vit D, and Xanax as needed. Resections in 2002 and 2005. Also diagnosed with Fibromyalgia, Osteoarthritis, and Anxiety. Currently my Crohns is in remission, but my joints are going crazy!
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Rider Fan
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Date Joined May 2008
Total Posts : 1445
   Posted 11/30/2009 9:23 AM (GMT -7)   
GDen said...
Think there's any dangers of long-term acetaminophen use? I've take it almost every day, usually no more than 1/4 to 1/2 the recommended max dose. I've encountered several people that think there may be hazards, but I haven't found anything official saying so. I did find several statements from drug companies saying acetaminophen is quite safe, even long-term, when directions are followed. I get LFTs every 2-4 weeks, and they've all been fine.
If your LFT's are fine and you're taking them under supervision of a dr. I wouldn't worry about it.  Our options for pain meds are pretty limited, so if you need to take something there isn't much else you can do anyway.
33 y/o male. Dx'ed in 1999. No surgeries.

Current meds: Humira 2/27/09. Proferrin iron pills.

Tried SCD, didn't work, now avoiding gluten and dairy.


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not creative
Regular Member


Date Joined Mar 2007
Total Posts : 466
   Posted 11/30/2009 10:03 AM (GMT -7)   
My CR surgeon told me that you're ok up to Four Grams a day- which is equivalent to what they put at the max dose. It's something like 8 500mg pills a day.
Laurenne, 25 Graduate from University of California, Davis. BA-Anthropology
Dx'd w/ IBS and CD in 2002. Three abscesses that are now fistulas, with three setons!
On: 6MP, Zoloft, Cimzia (working so well, I'm on Miralax too!), folic acid, b12
Tried: LDN- Did nothing good, Remicade- allergic, Humira- no reaction


Howlyncat
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Date Joined Jan 2005
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   Posted 1/12/2010 8:15 AM (GMT -7)   
i get liver function tested every 6 mths as i take tylenol 4 which has eq of 60 mgs of codeine and acetaminophen as well.....i take 1 and a hakf every 4 to 6 hrs......got off morphine n oxycontin due to issues i was having..
                          
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